丹参酮ⅡA防治老年放射性脑损伤临床观察

Clinical observation on Tanshinone ⅡA in radiation induced senile Brain injury

目的:观察丹参酮ⅡA防治老年放射性脑损伤临床疗效。方法:回顾性分析108例脑转移瘤丹参酮ⅡA联合放疗和104例脑转移瘤单纯放疗的老年脑转移患者的放射性脑损伤发生情况。结果:丹参酮ⅡA联合放疗组与单放疗组在防治放射性脑损伤方面差异有统计学意义(P<0.05)。结论:丹参酮ⅡA对老年脑转移瘤的放射治疗具有一定的辐射防护作用。

Objective：To observation the protective effect of Tanshinone ⅡA in radiation-induced senile brain injury.Methods：To compare 108 patients treated by Tanshinone ⅡA combined radiotherapy for brain metastases to 104 patients treated by radiotherapy alone.Results：The patients treated by Tanshinone IIA combined radiotherapy had significantly benefit in radiation brain injury with the patients treated by radiotherapy alone respectively（P0.05）.Conclusion：Tanshinone IIA can inhibit radiation-induced brain injary.