甲状腺全切除术治疗分化型甲状腺癌(附72例)

Total thyroidectomy in differentiated thyroid carcinoma:a report of 72 cases

目的:探讨甲状腺全切除术治疗分化型甲状腺癌安全性的相关因素。方法:回顾性分析本院2002年1月至2010年1月期间72例甲状腺全切术治疗分化型甲状腺癌的病历资料,分析甲状旁腺功能减退和喉返神经损伤的发生情况。结果:甲状旁腺功能减退发生与再次手术、原发肿瘤腺体外侵犯、中央区淋巴结转移有关,与是否行颈清无关;喉返神经的损伤与上述因素无关。结论:影响甲状腺全切术治疗分化型甲状腺癌安全性的相关因素有:手术次数、原发肿瘤腺体外侵犯和中央区淋巴结转移。

Objective：To explore the influential factors of undergoing total thyroidectomy in differentiated thyroid carcinoma.Methods：The data of laryngeal recurrent nerve injury and hypoparathyroidism in 72 patients with differentiated thyroid carcinoma after total thyroidectomy from 2002 to 2010,were retrospectively studied.Results：The hypoparathyroidism were significantly related to the times of thyroid operation,lymph nodes metastases of central compartment and the extraglandular invasion of primary tumor（P0.05）,and irrelative to the dissection of neck lymph nodes.The laryngeal recurrent nerve injury was irrelative to those factors（P0.05）.Conclusion：The influential factors of total thyroidectomy in differentiated thyroid carcinoma includes the times of thyroid operation,the lymph nodes metastases of central compartment and the extraglandular invasion of primary tumor.