外生型肝癌的临床特点及诊治

Clinic features,diagnosis and treatment of extrahepatic growing hepatocellular carcinoma

目的总结外生型肝癌的临床特点及诊治方法,探讨其定义及分型。方法在中文生物医学期刊文献数据库和中国医院知识仓库,应用主题词和作者联合检索外生型肝癌1994-2010年的文献报告,结合我院收治的病例,进行总结分析。结果获得有效文献55篇,共报道外生型肝癌352例,加上我院收治的35例,总共387例。外生型肝癌的诊断主要依靠临床表现、AFP、B超、CT、MRI、肝动脉造影及病理进行综合分析。结论外生型肝癌具有独特的临床病理特点,误诊率高,不易早期诊断。手术是首选治疗方法。

Objective To evaluate the clinical features,diagnosis,treatment,definition and classification of extrahepatic growing hepatocellular carcinoma（HCC）.Methods To review the reports of extrahepatic growing hepatocellular carcinoma in CNKI and CCMI from 1994 to 2010,these reports and the clinical data of patients with extrahepatic growing hepatocellular carcinoma treated in our hospital were analyzed.Results We acquired 387 patients including 35 patients in our hospital and 352 patients in 55 pieces of reports.Diagnosis of extrahepatic growing hepatocellular carcinoma mostly relied on comprehensive diagnosis based on clinical manifestations,AFP,B ultrasonography,CT,MRI,hepatic arteriography and pathological diagnosis.Conclusion Because of the special clinical and pathological features,extrahepatic growing hepatocellular carcinoma is easy to be misdiagnosed and it is difficult to be diagnosed early.Operation is the first selected therapeutic method.