期刊文献+

核苷(酸)类似物抗病毒治疗慢性乙型肝炎的优化策略 被引量:5

Optimized strategy for chronic hepatitis B patients receiving nucleos(t)ide analogue antiviral treatment
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摘要 目前我国有4种核苷(酸)类似物可用于慢性乙型肝炎(乙肝)的抗病毒治疗,即拉米夫定、阿德福韦酯、恩替卡韦和替比夫定。但由于患者的性别、年龄、遗传背景、感染乙肝病毒(HBV)的途径、病毒基因型、病程长短、
作者 庄辉 翁心华
出处 《中国病毒病杂志》 CAS 2011年第2期139-142,共4页 Chinese Journal of Viral Diseases
关键词 肝炎 乙型 慢性 优化治疗 路线图 核苷(酸)类似物 Hepatitis B chronic Optimal treatment Roadmap Nucleos(t)ide analogue
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参考文献17

  • 1董南,何波,庄辉.慢性乙型肝炎患者对疾病和抗病毒治疗的认知程度调查[J].肝脏,2009,14(1):8-10. 被引量:46
  • 2Hee Bok Chae,Hie-Won Hann.Baseline HBV DNA level is the most important factor associated with virologic breakthrough in chronic hepatitis B treated with lamivudine[J].World Journal of Gastroenterology,2007,13(30):4085-4090. 被引量:19
  • 3Yuen MF,Lai CL.Telbivudine for chronic hepatitis B:the GLOBEtrial. Future Virol . 2008
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  • 6Hsu CW,Chen YC,Liaw YF,et al.Prolonged efficacy andsafety of 3 years of continuous telbivudine treatment in pooleddata from GLOBE and 015 study in chronic hepatitis B patients. Journal of Hepatology . 2009
  • 7Jia JD,Gane E.Prolonged efficacy and safety of 4 years contin-uous telbivudine treatment in chronic hepatitis B (CHB)pa-tients from GLOBE and 015 studies. Hepatol Int . 2010
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二级参考文献21

  • 1慢性乙型肝炎防治指南[J].肝脏,2005,10(4):348-357. 被引量:272
  • 2Hoofnagle JH, Doo E, I.iang TJ, et al. Management of hepatitis B: Summary of a clinical research workshop. Hepatology, 2007, 45:1056-1075.
  • 3Lok ASF, McMahon BJ. Chronic hepatitis B. Hepatology, 2007, 45:507-539.
  • 4[1]Chang TT,Lai CL,Chien RN,Guan R,Lim SG,Lee CM,Ng KY,Nicholls GJ,Dent JC,Leung NW.Four years of lamivudine treatment in Chinese patients with chronic hepatitis B.J Gastroenterol Hepatol 2004; 19:1276-1282
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  • 8[5]Kanwal F,Gralnek IM,Hays RD,Dulai GS,Spiegel BM,Bozzette S,Asch S.Impact of chronic viral hepatitis on health-related quality of life in HIV:results from a nationally representative sample.Am J Gastroenterol 2005; 100:1984-1994
  • 9[6]Lok AS,Zoulim F,Locarnini S,Mangia A,Niro G,Decraemer H,Maertens G,Hulstaert F,De Vreese K,Sablon E.Monitoring drug resistance in chronic hepatitis B virus (HBV)-infected patients during lamivudine therapy:evaluation of performance of INNO-LiPA HBV DR assay.J Clin Microbiol 2002; 40:3729-3734
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