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心包内脂肪 被引量：2

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摘要 内脏性肥胖与原发性高血压、糖尿病、血脂代谢异常等多种心血管疾病的危险因素密切相关。与非肥胖个体比较，内脏肥胖者心肌梗死发病率更高，冠状动脉粥样硬化进展更快，即使在具有相同脂肪总量的人群中，由于人体的脂肪分布不同，其发生心血管疾病的危险性并不相同，内脏型肥胖患者预后更差，病死率增加更明显[1]。心包内、外脂肪是沉积在心脏周围的内脏脂肪组织，尽管在19世纪中叶解剖学家已经认识到心包和大血管周围有脂肪组织存在，
作者 吴坚 杨立
机构地区 解放军总医院放射科北京
出处 《中国医学影像学杂志》 CSCD 北大核心 2011年第4期259-262,共4页 Chinese Journal of Medical Imaging
关键词 心包 脂肪组织 冠状动脉硬化 细胞因子类
分类号 R542.1 [医药卫生—心血管疾病]
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参考文献28

  • 1Rosito GA, Massaro JM, Hoffmann U, et al. Pericadial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in community-based sample: the Framingham Heart Study. Circulation, 2008, 117(5): 605-613.
  • 2Iacobellis G, Leonetti F. Epicardial adipose tissue and insulin resistance in obese subjects. J Clin Endocrinol Metab, 2005, 90(11): 6300-6302.
  • 3Rabkin SW. Epicardial fat: properties, function and relationship to obesity. Obes Rev, 2007, 8(3): 253-261.
  • 4Silaghi A, Piercecchi-Marti MD, Grino M, et al. Epicardial adipose tissue extent: relationship with age, body fat distribution and coronaropath. Obesity, 2008, 16(11): 2424- 2430.
  • 5Corradi D, Maestri R, Callegari S, et al. The ventricular epicardial fat is related to the myocardial mass in normal, ischemic and hypertrophic hearts. Cardiovasc Pathol, 2004, 13(6): 313-316.
  • 6Iacobellis G, Assael F, Ribaudo MC, et al. Epicardial fat from echocardiography: a new method for visceral adipose tissue prediction. Obes Res, 2003, 11(2): 304-310.
  • 7Kankaanpaa M, Lehto H-R, Parkka JP, et al. Myocardial triglyceride content and epicardial fat mass in human obesity: relationship to left ventricular function and serum free fatty acid levels. J Clin Endocrinol Metab 2006, 91(11) 4689-4695.
  • 8Willens H J, Byers P, Chirinos JA, et al. Effects of weight loss after bariatric surgery on epicardial fat measured using echocardiography. Am J Cardiol, 2007, 99(9): 1242-1245.
  • 9Teranishi T, Ohara T, Maeda K, et al. Effects of pioglitazone and metforminonintracellular lipid content in liver and skeletal muscle of individuals with type 2 diabetes mellitus. Metabolism, 2007, 56(10): 1418-1424.
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同被引文献28

  • 1穆守刚,张敏,赖兆新,周新明.心包外脂肪层的临床分析[J].中国现代医药杂志,2007,9(4):56-59. 被引量：3
  • 2Jensen MD. Adipose tissue as an endocrine organ:implications of its distribution on free fatty acid metabolism. Eur Heart J. 2006, 8(Suppl B): B13-B19.
  • 3Mazurek T, Zhang L, Zalewski A, et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation, 2003, 108(20): 2460-2466.
  • 4Iacobellis G, Pistilli D, Gucciardo M, et al. Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease. Cytokine, 2005, 29(6): 251-255.
  • 5Ahn SG, Lira HS, Joe DY, et al. Relationship of epicardial adipose tissue by echocardiography to coronary artery disease. Heart, 2008, 94(3): e7.
  • 6Jeong JW, Jeong MH, Yun KH, et al. Echocardiographic epicardial fat thickness and coronary artery disease. Circ J, 2007, 71(4): 536-539.
  • 7Gorter PM, de Vos AM, van der Graaf Y, et al. Relation of epicardial and pericoronary fat to coronary atherosclerosis and coronary artery calcium in patients undergoing coronary angiography. Am J Cardiol, 2008, 102(4): 380-385.
  • 8Alexopoulos N, Mclean DS, Janik M, et al. Epicardial adipose tissue and coronary artery plaque characteristics. Atherosclerosis, 2010, 210( 1 ): 150-154.
  • 9Park JS, Choi SY, Zheng M, et al. Epicardial adipose tissue thickness is a predictor for plaque vulnerability in patients with significant coronary artery disease. Atherosclerosis, 2013, 226(1): 134-139.
  • 10Cheng VY, Dey D, Tamarappoo B, et al. Pericardial fat burden on ECG-gated noncontrast CT in asymptomatic patients who subsequently experience adverse cardiovascular events. JACC Cardiovasc Imaging, 2010, 3(4): 352-360.

引证文献2

二级引证文献6

中国医学影像学杂志
2011年 第4期

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