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血小板糖蛋白Ⅱb／Ⅲa受体抑制剂临床应用进展 被引量：6

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摘要 直接经皮冠状动脉介入治疗（percutaneous coronary intervention，PCI）后仍有5％～50％的患者达不到最佳再灌注，影响患者远期预后[1]。血小板糖蛋白Ⅱb／Ⅲa受体抑制剂（glycoprotein Ⅱb／Ⅲa receptorinhibitors，GPI）可以阻断血小板聚集的最终共同通路，减少PCI后无复流的发生率[2]。美国心脏病学院／美国心脏学会（ACC／AHA）的ST段抬高型心肌梗死（ST elevation myocardial infarction，STEMI）治疗指南”。
作者 周鹏 颜红兵
机构地区 首都医科大学研究生院 中国医学科学院北京协和医学院阜外心血管病医院冠心病诊治中心
出处 《中华心血管病杂志》 CAS CSCD 北大核心 2011年第3期274-277,共4页 Chinese Journal of Cardiology
基金 首都医学发展科研基金（2009-2076）
关键词 血小板糖蛋白Ⅱb/Ⅲa受体抑制剂 临床应用 直接经皮冠状动脉介入治疗 ST段抬高型心肌梗死 美国心脏病学院 美国心脏学会 血小板聚集 远期预后
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献28

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同被引文献41

  • 1杨新春,徐立,王乐丰,葛永贵,王红石,丁枭伟,王文君,邹阳春,李惟铭,刘宇.国产替罗非班对急性心肌梗死患者急诊介入治疗术后冠状动脉血流和心肌灌注影响的研究[J].中国循环杂志,2006,21(1):4-7. 被引量：91
  • 2沈杰,沈卫峰.替罗非班在急性冠脉综合征介入治疗中的应用[J].国际心血管病杂志,2006,33(3):156-159. 被引量：72
  • 3Lee YW,Kim HJ,Cho YH,et al. Application c f albumin adjusted ischemia modified Albumin index as an early screening marker for acute coronary syndrome[J]. Clin Chim Acta, 2007, 384 : 24 27.
  • 4De Luca G,Ucci G Cassetti E,et al. Benefits from small molecule administration As compared with abciximab among patients with ST-seg ment elevation myocardial Infarction treated with primary angioplasty: a meta-analysis[J]. J Am Coil Cardiol, 2009,53 : 1668-1673.
  • 5Virmani R, Burke AP, Farb A, et al. Pathology of the vulnerablep laque [J]. J Am Coil Cardiol, 2006, 47 ( Suppl): C13-C18.
  • 6McClellan K J, Goa KL, Tirofiban. A review of its use in acute coro- nary syndromes[J]. Drugs, 1998,56 ( 6 ): 1067- 1080.
  • 7张邑,杜春丽,于学军,等.小剂量替罗非班在急性冠脉综合征药物保守治疗中的安全性及有效性[J].药物研究,2010,19(7):2559-2561.
  • 8Helen Johansen, Susan E Brien, Philippe Fin~ s, et al. Thirty-day in-hospital revascularization and mortality rates atter acute myocardial infarction in seven Canadian provinces [J]. The Canadian journal of cardiology, 2010,26(7): e243-e248.
  • 9Cruz-Gonzalez I, Sanchez-Ledesma M, Baron S J, Healy JL, et al. Effi- cacy and safety of argatroban with or without glycoprotein IIb/IIIa in- hibitor in patients with heparin induced thrombocytopenia undergoing percutaneous coronary intervention for acute coronary syndrome [J]. Journal of Thrombosis and Thrombolys,2008, 25(2):214-218.
  • 10ACC/AHA 2007guidelines for the manangement of patients with un- stable angina/non-ST-Elevation myocardial infarction [J]. J Am Coil Cardiol, 2007, ( 50 ) :el-E1157.

引证文献6

中华心血管病杂志
2011年 第3期

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