负压创面疗法应用于深Ⅱ度烧伤创面的临床观察

A preliminary study on deep second degree burn wound treated by negative pressure wound therapy

目的研究负压创面疗法(NPWT)对于深Ⅱ度烧伤创面的治疗作用。方法采用NPWT治疗19例患者,共22个深Ⅱ度烧伤创面。观察坏死组织清除情况,记录伤后10、14、21、28d创面愈合率和创面完全愈合时间。结果 NPWT治疗后,观察的22个创面中有18个创面的坏死组织被全部清除,其余4个创面表面坏死组织被部分清除。创面愈合率在伤后10、14、21、28d分别为(44±27)%,(69±28)%,(90±13)%,(100±0)%。创面完全愈合时间为(20.1±4.9)d,1个创面最后通过手术封闭,其余创面均通过换药愈合。结论 NPWT具有加速深Ⅱ度创面愈合的作用,对坏死组织有效地清除可能是其重要机制之一。

Objective To study the therapeutic effects of negative pressure wound therapy （NPWT） on deep second degree burn wound. Methods Nineteen patients including 22 deep second degree burn wounds received the treatment of NPWT. Necrotic tissue clearance, wound healing rate and time to complete wound healing were determined. Results The necrotic tissue of 18 burn wounds in 22 burn wounds was totally removed after NPWT. Wound healing rate was 44% ±27%, 69% ±28%, 90% ±13%, 100% ±0% in 10 days, 14 days, 21 days, and 28 days postburn respectively. Time to complete wound healing was 20.1 ±4.9 days. Only one of the 22 burn wounds was healed by operation. Conclusion NPWT inproves the wound healing of deep second degree burn, and the effective removal of the necrotic tissue could be one of its main mechanisms.