ICU感染患者致病微生物110例临床分析

Clinical analysis on pathogenic microorganisms in 110 cases of infection in ICU

目的探讨重症监护室(ICU)院内感染者的常见致病微生物临床特点及其治疗途径。方法通过回顾ICU及普通病房感染患者各110例的临床资料,分析院内感染的发病率、分布情况以及致病微生物的种类及其耐药性。结果 ICU内的主要致病微生物是肺炎克雷伯菌和铜绿假单胞菌,且其耐药性在ICU病房内明显增加,β内酰胺酶阳性菌与普通病房比较增多,真菌与院内感染率均明显增加。结论 应加强ICU管理,预防院内感染,同时合理应用抗生素,延缓耐药菌产生。

Objective To explore the clinical features of common pathogenic microorganisms in patients infected in ICU ward,and to evaluate their therapeutic approaches.Methods The clinical data of 110 patients infected in ICU and general wards were retrospectively reviewed and analyzed,and the incidence rate of nosocomial infection,distribution and types of pathogenic microorganisms and drug resistance were discussed.Results The main causative microorganisms in ICU ward were Klebsiella pneumoniae and Pseudomonas aeruginosa,and their resistance to drugs was significantly increased in ICU ward,and ESBL-positive bacteria were increased in comparison with those in general ward,and the rates of fungal and nosocomial infections were significantly higher than those of general wards.Conclusion The management,prevention of nosocomial infection and rational application of antibiotics should be strengthened in ICU ward in order to slow down the generation of drug resistance in pathogenic microorganisms.