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左旋门冬酰胺酶致儿童弥散性血管内凝血(DIC)死亡1例 被引量:1

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摘要 左旋门冬酰胺酶(L-asparaginase,L-asp)是临床主要使用的抗肿瘤药物之一,也是治疗儿童急性淋巴细胞白血病(acute lymphocyticleukemia,ALL)的主要药物之一,近10多年,由于采用了左旋门冬酰胺酶的联合化疗方案,使得急性淋巴细胞白血病患者的长期存活率有显著提高,亦使一些难治性急性髓性白血病获得缓解甚至长期生存,加上左旋门冬酰胺酶对骨髓抑制较轻,为此临床上应用此药较广。但其不良反应如过敏反应、肝损害、胰腺炎、食欲减退,
作者 张馨予
出处 《中国医药指南》 2011年第13期141-142,共2页 Guide of China Medicine
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  • 9顾龙君,赵惠君,陈静,郑伟敏.去甲氧柔红霉素联合方案治疗难治性急性淋巴细胞白血病的远期疗效[J].中华儿科杂志,1998,36(1):5-7. 被引量:8

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