白介素4在支气管哮喘发病机制中的作用及其靶向治疗研究

Function and targeted therapy of interleukin-4 in bronchial asthma

支气管哮喘（简称哮喘）发病率正逐年上升，其发病机制十分复杂。目前认为Th1／Th2反应失衡导致Th2细胞增多是其重要的发病机制之一，其中Th2细胞产生的细胞因子白介素4在哮喘发病中起重要的作用，成为新的哮喘治疗靶点。

The incidence of Bronchial asthma （asthma） is increasing year hy year, hesides, the pathogenesis is very complex. Nowadays, it is believed that imbalance of Th1/Th2 response leading to excessively create of Th2 cells is one of the important pathogenesis. IL-4 produced by Th2 cells play an important role in asthma, understanding IL-4 in asthma may lead to new target to therapy in the future.