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无痛准分子激光角膜上皮瓣下磨镶术的临床研究 被引量:5

Painless laser epithelial keratomileusis clinical study
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摘要 目的探讨控制准分子激光上皮瓣下角膜磨镶术(LASEK)术后疼痛及炎症反应的方法,评价无痛LASEK的可能性。方法常规LASEK为2006年6月1日至2007年6月1日手术者;无痛LASEK为2008年6月1日至2009年6月1日手术者。应用了更为熟练而稳妥的操作,增加了术前、术中、术后非类固醇消炎药普拉洛芬滴眼液的应用等措施。两组各160例(320眼),随访时间均为1a。观察两组畏光、流泪、异物感、疼痛以及裂隙灯显微镜观察的情况,各项指标得分相加后得到综合评分,比较两组在术后即刻、术后2d,术后6d,术后14d在综合评分差异。结果无痛LASEK组和常规LASEK组综合评分在术后即刻,术后2d差别有统计学意义。术后6d及14d差别无统计学意义。症状消失的天数差别有统计学意义。结论无痛性LASEK控制LASEK术后疼痛及炎症反应有效而安全。可以达到无痛LASEK的要求。 Objective To explore the efficacy and safety of painless laser epithelial keratomileusis for controlling LASEK postoperative pain and inflammation. Methods 160 patients (320 eyes) accepted conventional LASEK from June 1,2006 to June 1,2007, painless LASEK from June 1,2008 to June 1,2009. and followed up for one year to observe the result of photophobia, tearing, foreign body sensation, pain, and slit lamp at immediately, then get integrated score, Comparing the composite score between the two groups, at immediately, 2d postoperatively, 6 d postoperatively, 14 d postoperatively. Results Painless LASEK and LASEK group showed statistic significant difference at immediately and 2 d postoperatively but not differ ent at 6 d and 14 d postoperatively. The number of days with no symptoms were significantly different. Con clusions It is safe and effective to use painless LASEK for controlling the pain and inflammation after the LASEK.
出处 《中华眼外伤职业眼病杂志》 2011年第4期268-271,共4页 Chinese Journal of Ocular Trauma and Occupational Eye Disease
关键词 准分子激光角膜上皮瓣下磨镶术 无疼痛 Laser epithelial keratomileusis Painless
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  • 1邹俊,周行涛,戴锦晖,褚仁远.中低度近视的准分子激光上皮瓣下角膜磨镶术[J].中国实用眼科杂志,2005,23(6):616-619. 被引量:14
  • 2Hondur A,Bilgihan K,Hasanreisoglu B.A prospective bilateral comparison of Epi-LASIK and LASEK for myopia Journal of Refractive Surgery,2008,24:928-934.
  • 3Arbelaez MC vidal C,Arba Mosquera S.et al.Comparison of LASEK and LASIK with thin and ultrathin flaps after excimer laser ablation with the schwind aspheric ablation profile.Journal of Refractive Surgery,2010,28:1-11.
  • 4Pallikaris IG,Katsanevaki VJ,Knlyvianaki MI.et al.al.Advances insubepithelial excimer refractive surgery techniques:epi-LASIK.Curr Opin Ophthalmol,2003,14:207-212.
  • 5McAlinden C,Moore J.Laser-assisted subepithelial keratectomy retreatment surgery.Journal of cataract and refractive surgery.37:358-363,2011.
  • 6Saeed A,O' Doherty M,O' Doherty J,et al.laser-assisted subepithelial keratectomy retreatment after laser in situ keratomileusis,journal of cataract and refractive surgery.2008,34:1736-1741.
  • 7Qazi MA,Sanderson JP,Mahmoud AM,et al.Postoperative changes in intraocular pressure and corneal biomechanical metrics Laser in situ keratomileusis versus laser-assisted subepithelial keratectomy.Journal of cataract and refractive surgery.2009,35:1774-1788.
  • 8Tietjen A,Müller C,Sekundo W.A prospective intraindividual comparison between laser in situ keratomileusis and laser subepithelial keratectomy for myopia:1-year follow-up results.Der Ophthalmologe:Zeitschrift der Deutschen Ophthalmologischen Gesellschaft.2008,105:921-926.
  • 9Reilly CD.Panday V.Lazos V.et al.PRK vs LASEK vs EpiLASIK:A comparison of corneal haze,postoperative pain and visual recovery in moderate to high myopia.Nepalese journal of Ophthalmology:a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society:NEPJOPH,2010,2:97-104.
  • 10Hondur A,Bilgihan K,Hasanreisoglu B.A prospective bilateral comparison of epi-LASIK and LASEK for myopia.Journal of refractive surgery(Thorofare,N.J:1995)2008,24:928-934.

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