高血压病患者大脑中动脉血流量测定结果分析

Examination of Blood Flow Volume of Middle Cevebral Arteny of Patients with Hypertention

采用经颅彩色双功超声（ＴＣＣＤ）检测了３６ 例Ⅰ、Ⅱ期高血压病患者（观察组）的大脑中动脉（ＭＣＡ）血流量，并与８０ 例正常成年人（对照组）进行比较。结果显示，高血压病患者降压治疗前ＭＣＡ血流速度、管径和血流量的异常率分别为５１．４％ 、４５．８％ 和６２．５％ ，Ⅰ期患者以血流速度增快、管径缩小为主，Ⅱ期则以血流速度减慢、管径变大为多见；Ⅰ、Ⅱ期患者ＭＣＡ 血流量分别有３４．２％ 和４４．１％ 低于正常；高血压病患者降压治疗１周时ＭＣＡ血流量较治疗前下降（Ｐ＜ ０．０１）。提示对于ＭＣＡ血流量下降的高血压病患者降压治疗宜从小剂量开始，以防止发生脑缺血改变。

The blood flow volume of middle cerebral artery(MCA)of 36 patients with hypertention(Ⅰ and Ⅱ stage)and 80 normal adult volunteers were examined by transcranial color duplex sonography(TCCD) The result showed that the abnornal rates of blood flow velocity,vessel diameter and blood flow volume of the MCA of patients with hypertention were 51 4%,45 8% and 62 5% respectively Most patients with Ⅰ stage hypertension were found having vasospasm of MCA and patients with Ⅱ stage hypertension mainly having MCA angiectasis The blood flow volume of MCA in 34 2% Ⅰ stage and 44 1% in Ⅱ stage hypertensive patients was lower than normal It was also found that blood flow volume of the MCA of hypertensive patients decreased after one week of antihypertensive treatment