摘要
目的:评估高效液相色谱(HPLC)法测定阿莫西林含量的测量不确定度。方法:建立HPLC法测定含量的数学模型,分析测量不确定度的来源,量化各个测量不确定度分量,合成标准测量不确定度,给出扩展测量不确定度报告。结果:HPLC法测定阿莫西林含量的扩展测量不确定度为1.62%,测量结果表示为(87.32±1.62)%,k=2。结论:HPLC法测定阿莫西林含量的测量不确定度评估,方法简单合理,保证了测量结果准确可靠。
OBJECTIVE： To evaluate the measurement uncertainty for the content determination of amoxicillin by HPLC. METHODS： The model of content determination by HPLC was established, then the uncertainty sources had been analyzed. Each active components of uncertainty was calculated, and the extended uncertainty was obtained. RESULTS： The extended uncertainty for the HPLC determination of amoxicillin was 1.62%, the results of content determination was （87.32±1.62）%, k=2. CONCLUSION： The evaluation method of measurement uncertainty for the content determination of amoxicillin by HPLC is convenient and reasonable to guarantee the accurate and reliability of the results.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第20期1910-1912,共3页
China Pharmacy
