手术治疗大肠癌肝转移的疗效分析及预后因素探讨

The therapeutic effect and the prognostic factors of liver lesection for colorectal hepatic metastases.

目的 探讨大肠癌术后肝转移手术切除的疗效及影响术后生存率的有关因素，总结改进远期疗效的措施。方法 对８７ 例大肠癌肝转移病人术后进行长期随访，并对治疗中相关因素进行统计分析，对比研究。结果 全组术后１ 、３ 、５ 年生存率分别为７７．０ ％ 、３２．２ ％ 和２４．１ ％ 。统计分析表明，原发癌病理类型，病灶数目、手术方式及时机选择，术后治疗等是影响术后长期生存的重要因素。结论 早发现早切除，改进治疗中的相关因素，术后密切监测，发现早期复发和转移。

Objective\ To study the therapeutic effect,the prognostic factors and the ways to improve long term survival of liver resection for colorectal hepatic metastases.Methods\ After surgery for colorectal cancer,87 patients with liver metastases were followed up for a long time.Tumor grading,tumor staging,type of resection and postoperative multimedia treatment were summarized.Some relative factors were analyzed statistically and studied contrastedly.Results\ The 1-,3-and 5-year survivals were 77 0%,32 2% and 24 1%respectively.According to the statistical results,the pathologic style of primary cancer,number of tumor,how and when to perform surgery,and postoperative treatment are important factors affecting long term survival.Conclusions\ The cruxes to improve healing power are:early diagnosis and resection,ameliorating some relative factors,intensive postoperative examination,detection of early relapse,repeat resection of recurrence,and postoperative multimedia treatment.