Bmi-1与干细胞及肿瘤干细胞关系的研究进展

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摘要多梳基因Bmi-1属PcG家族的一员，其可导致某些抑癌基因失活并为调节肿瘤干细胞的自我更新和分化所必需，可以作为肿瘤干细胞分选扩增的分子标记物。现在很多肿瘤都可以分离出致瘤能力强、有自我更新和分化潜能的细胞称为肿瘤干细胞，本文对Bmi-1基因在干细胞及肿瘤干细胞方面的研究进展进行综述。

作者崔学江朱定军韩金利梁武苏嘉锐谢文练

机构地区广州中山大学孙逸仙纪念医院泌尿外科

出处《国际泌尿系统杂志》 2011年第3期320-323,共4页 International Journal of Urology and Nephrology

基金 2010年国家自然基金面上项目项目批准号：81072102

关键词肿瘤干细胞基因

参考文献26

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国际泌尿系统杂志

2011年第3期

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