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西罗莫司在肾脏病中的应用新知

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摘要 西罗莫司主要应用于器官移植,近年来发现在原发性肾小球疾病、继发性肾小球疾病、非糖尿病慢性肾脏病、常染色体显性遗传多囊肾疚病和肾细胞癌等疾病均具有疗效好、不良反应轻等特点。
机构地区 济南市解放军第
出处 《国际泌尿系统杂志》 2011年第3期411-414,共4页 International Journal of Urology and Nephrology
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  • 1Bhaskar PT,Hay N.The two TORCs and Akt.Dev Cell.2007 Apr;12(4):487-502.
  • 2Dunlop EA,Dodd KM,Seymour LA,Tee AR.Mammalian target of rapamycin complex 1-mediated phogphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein-protein interactions for substrate recognition.Cell Signal.2009 Jul;21 (7):1073 -1084.
  • 3Pearce LR,Huang X,Boudeau J,et al.Identification of Protor as a novel Rictor-binding component of mTOR complex -2.Biochem J.2007 Aug 1;405(3):513-522.
  • 4Dowling RJ,Topisirovic I,Fonseca BD,et al.Dissecting the role of mTOR:lessons from mTOR inhibitors.Biochim Biophys Acta.2010 Mar;1804(3):433-439.
  • 5Hoeffer CA,Klann E.mTOR signaling:at the crossroads of plasticity,memory and disease.Trends Neurosci.2010 Feb;33(2):67-75.
  • 6Cuertin DA,Sabatini DM.The pharmacology of mTOR inhibition.Sci Signal.2009 Apr 21 ;2(67):pe24.
  • 7Lieberthal W,Levine JS.The role of the mammalian target of rapamycin (mTOR) in renal disease.J Am Soc Nephrol.2009 Dec;20 (12):2493-502.
  • 8Tumlin JA,Miller D,Near M,et al.A prospective,open-label trial of Sirolimus in the treatment of focal segmental glomerulosclerosis.Clin J Am Soc Nephrol.2006; 1:109-116.
  • 9Fervenza FC,Fitzpatrick PM,Mertz J,et al.Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies.Nephrol Dial Transplant.2004 May;19(5):1288 -1292.
  • 10Jose Miguel L,Vallejo GV.Case report:Corticosteroid -resistant nephrotic syndrome:treatment with rapamune.Pediatr Nephrol.2007 Feb;22(2):315-316.

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