期刊文献+

孟鲁司特钠、沙丁胺醇联合布地奈德治疗小儿咳嗽变异性哮喘的疗效观察 被引量:24

下载PDF
导出
摘要 目的探讨孟鲁司特钠、沙丁胺醇联合布地奈德气雾剂治疗小儿咳嗽变异性哮喘的临床疗效。方法将笔者所在医院收治的86例咳嗽变异性哮喘患儿按不同的治疗方法分为两组,比较两组的患儿的临床疗效及临床缓解时间。结果治疗组临床治愈率明显高于对照组,治疗组症状缓解及症状消失时间明显少于对照组。两组患者治疗过程中均未见明显不良反应。结论孟鲁司特钠、沙丁胺醇联合布地奈德气雾剂治疗小儿咳嗽变异性哮喘的疗效满意,起效快,无明显不良反应,值得临床推广应用。
作者 肖并
出处 《中国医学创新》 CAS 2011年第13期139-140,共2页 Medical Innovation of China
  • 相关文献

参考文献3

二级参考文献11

  • 1LEE KS,KIM SR,PARK HS,et al.Cysteinyl leukotriene receptor antagonist regulates vascular permeability by reducing vascular endothelial growth factor expression[J].J Allergy Clin lmmunol,2004,114(5):1093-1099.
  • 2KARAMAN O,SUNNELI L,UZUNER N,et al.Evaluation of montelukast in 8 to 14 year old children with mild persistent asthma and compared with inhaled corticosteroids[J].Allergol Immunopathol (Madr),2004,32 (1):21-27.
  • 3CIPRANDI G,TOSCA MA,MILANESE M,et al.Antihistamines added to an antileukotriene in treating seasonal allergic rhinitis:histamine and leukotriene antagonism[J].Allerg Immunol (Paris),2004,36(2):67 -70,72.
  • 4KITCHEN CJ,WANG AQ,MUSSON DG,et al.A semi-automated 96-well protein precipitation method for the determination of montelukast in human plasma using high performance liquid chromatography/fluorescence detection[J].J Pharm Biomed Anal,2003,31 (4):647 -654.
  • 5AL-RAWITHI S,AL-GAZLAN S,AL-AHMADI W,et al.Expedient liquid chromatographic method with fluorescence detection for montelukast sodium in micro-samples of plasma[J].J Chromatogr B Biomed Sci Appl,2001,754 (2):527 -531.
  • 6MIGOYA E,KEARNS GL,HARTFORD A,et al.Pharmacokineticsof montelukast in asthmatic patients 6 to 24 months old[J].J Clin Pharmacol,2004,44 (5):487-494.
  • 7KNORR B,LARSON P,NGUYEN HH,et al.Montelukast dose selection in 6-to 14-year-olds:comparison of single-dose pharmacokinetics in children and adults[J].J Clin Pharmacol,1999,39(8):786-793.
  • 8WALSKY RL,GAMAN EA,OBACH RS.Examination of 209 drugs for inhibition of cytochrome P450 2C8[J].J Clin Pharmacol,2005,45(1):68 -78.
  • 9DEPRE M,VAN HECKEN A,VERBESSELT R,et al.Effect of multiple doses of montelukast,a CysLT1 receptor antagonist,on digoxin pharmacokinetics in healthy volunteers[J].J Clin Pharmacol,1999,39(9):941 -944.
  • 10MALMSTROM K,SCHWARTZ J,Reiss TF,et al.Effect of montelukast on single-dose theophylline pharmacokineties[J].Am J Ther,1998,5(3):189 -195.

共引文献2657

同被引文献120

引证文献24

二级引证文献198

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部