缺血性脑卒中患者检测糖化血红蛋白和餐后2h血糖的价值

Study the Value of Glycosylated Hemoglobin and 2 Hours Postprandial Blood Glucose in Patients with Ischemic Stroke

目的:探讨缺血性脑卒中患者检测糖化血红蛋白(HbA lc)和餐后2h血糖(2hPBG)的价值,分析其与病情严重程度、预后的关系。方法:将120例缺血性脑卒中患者分为3组:正常血糖组、高血糖组、糖尿病组,测定餐后2h血糖、糖化血红蛋白。结果:餐后2h血糖、糖化血红蛋白高血糖组和糖尿病组较正常血糖组明显升高,差异有显著性(P(0.05)。高血糖组和糖尿病组较正常血糖组,缺血性脑卒中病情重,预后差,梗死面积大,死亡率高,差异有显著性(P(0.05)。结论:糖化血红蛋白水平和餐后2h血糖与缺血性脑卒中病情严重程度密切相关,可作为判断病情、估计预后的指标。

Objective：To investigate the value glycosylated hemoglobin（HbA1c） and 2h postprandial blood glucose（2hPBG） and assesse their relations to disease severity and prognosis in patients with ischemic stroke.Method：120 patients with ischemic stroke were divided into three groups,normal blood glucose group,high blood glucose group and DM group.2hPBG and HbAlc were measured in 120 patients.Result：HbAlc and 2hPBG in high blood glucose group and DM group were significantly higher than that in normal blood glucose group.There’s significant difference（P〈0.05）.There were severer disease severity,poorer prognosis,wider infarct size and higher mortality in high blood glucose group and DM group than those in normal blood glucose group.There’s with significant difference（P〈0.05）.Conclusin：HbAlc and 2hPBG is closely related to disease severity and could be as a significant indicator for evaluating disease severity and assessing prognostic of ischemic stroke.