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高血压病患者踝—臂脉搏波速度的影响因素及其对心脑血管事件的预警作用 被引量:1

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摘要 目的:探讨高血压病患者踝—臂脉搏波波传导速度(baPWV)的影响因素及其对远期心脑血管并发症的预警作用。方法:收集住院的高血压病患者171例,记录其基本病史资料、心血管危险因素、血压,心率、血脂、肾功能、C反应蛋白等生化指标及心脑血管并发症情况。按照baPWV=1 700 cm/s为界,将患者分为高、低baPWV两组,以分组的baPWV为因变量,上述因素为自变量,进行二分类非条件Logistic多因素回归分析,并比较两组心、脑等靶器官损伤的发病率。结果:经单因素Logis-tic回归分析,年龄、病程、收缩压、舒张压、脉压差、心率、总胆固醇、低密度脂蛋白、C反应蛋白、心血管危险因素聚集度、心脑血管并发症等因素与baPWV相关;多因素Logistic回归分析显示,年龄、收缩压、心率是baPWV的独立危险因素。与低baPWV组相比,高baPWV组心脑血管事件发生率较高(20.2%vs27.5%,P=0.037),心血管危险因素数目较多[(2.42±1.15)个vs(3.03±1.21)个,P=0.001],并且baPWV随着心血管危险因素聚集度的升高而加快。结论:高血压病患者的baPWV主要由年龄,收缩压,心率决定;且患者合并的心血管因素越多baPWV越高;具有较高baPWV的患者容易并发心脑血管事件。
出处 《广西医科大学学报》 CAS 2011年第1期103-106,共4页 Journal of Guangxi Medical University
基金 广西研究生教育创新计划资助项目(No.2009105981002M208)
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