碎米果镇痛抗炎的实验研究

An Experimental Study on the Analgesic and Anti-Inflammatory Effect of Myrsine Africana

目的:观察碎米果水煎液的镇痛、抗炎作用。方法:镇痛实验采用小鼠热板法、光热刺激法、醋酸致痛扭体法等实验方法;抗炎实验采用二甲苯所致小鼠耳肿胀方法及二甲苯所致小鼠皮肤毛细血管通透性增高的方法。结果:碎米果水煎液对小鼠热刺激致痛、光热刺激致痛及注入醋酸致痛均有抑制作用,还能降低二甲苯所致小鼠耳肿胀度及皮肤毛细血管通透性。结论:碎米果水煎液有一定镇痛、抗炎作用。

Objective:To observe the analgesic and anti-inflammatory effect of Myrsine africana.Methods: Analgesic experiments were mice hot plate,light and heat stimulation and the pain writhing caused by acetic acid and anti-inflammatory experiments were mice ear swelling induced by xylene and mice skin capillary permeability induced by xylene.Result:Myrsine africana decoction could inhibit the thermal stimulation pain and acid injection pain in mice and reduce the mice ear swelling and the skin capillary permeability induced by xylene.Conclusion:Myrsine africana decoction has some analgesic and anti-inflammatory effect.