中医综合疗法治疗斑块型银屑病的临床研究

Clinical Trail of Plaque Type Psoriasis by Combination Therapy of Traditional Chinese Medicine

目的观察中医综合疗法治疗斑块型银屑病的临床疗效,为探寻一种较好的治疗斑块型银屑病的方法。方法将入选的127例斑块型银屑病患者按门诊及住院顺序编号,采用随机数字表分成2组。治疗组为健脾解毒汤联合中药药浴、外用普连膏及走罐治疗;对照组为口服阿维A胶囊外用他扎罗汀软膏及联合窄谱中波紫外线(NB-UVB)治疗,2组均为2周为1疗程,3个疗程后判定疗效。结果治疗组有效率为95.71%,对照组为82%,治疗组疗效优于对照组,差异具有统计学意义(P<0.05)。治疗组复发率(13.64%),对照组复发率(25%),两组间差异无统计学意义(x2=0.2308,P>0.05),不良反应率治疗组(11.43%),对照组(56%),组间比较具有统计学意义(χ=14.44,P<0.01),治疗后治疗组与对照组PASI评分的比较具有统计学意义(P<0.01),中医综合组平均疗程4.54周,对照组平均病程5.5周。结论中医综合疗法治疗斑块型银屑病疗效较好,可缩短疗程,降低复发率及不良反应。

Objective To seek for a better therapy for plaque type psoriasis.Methods 127 patients were randomly divided into 2 groups：76 in treatment group and 50 in control group,treatment group received Jianpi Jiedu Decoction,Traditional Chinese Medical Herbs bath,Pulian emulsion and moving cupping.The control group received Tazarotene Cream,Acitretin Capsules,combined with narrow-band ultraviolet B （NB-UVB）.Results The total effective rate in the treatment group was 95.71% ,and the control group was 82.00% ,the treatment group was better than the control group and has significant difference （P 0.05）.the relapse rate has no-significant difference （χ2 = 0.2308,P 0.05 ）between two groups,and adverse effect rate in the treated group was 11.43% ,the control groups was 56% ,and has significant difference （χ2 = 14.44 ,P 0.01）,the score of PASI has significant difference （P 0.01）between two groups after treatment.Conclusion The effect of combination therapy of Traditional Chinese Medicine in Plaque Type Psoriasis has better effect,the course of treatment cuold be shorted,and advrese effece could be cut down.