中西医结合治疗充血性心力衰竭临床研究

Clinical Study on Congestive Heart Failure Treated with Integrative Chinese and Western Medicine

目的:探讨中西医结合治疗充血性心力衰竭(CHF)的临床疗效。方法:将60例患者随机分为两组,对照组为西药治疗,治疗组采用自拟中药心衰宁汤加西药治疗,并作对照观察。疗效评价以心功能分级与左室射血分数(LVEF)改善情况为标准。结果:治疗组30例中显效10例(33.3%),有效18例(60.0%),无效2例(6.7%),有效率93.30%;对照组30例中显效8例(26.7%),有效15例(50.0%),无效7例(23.3%),有效率76.70%。治疗组有效率与对照组比较差异有显著性(χ2=8.06,P<0.05)。同时治疗前后LVEF、心率等心功能指标均有明显改善,治疗组均优于对照组(P<0.05)。结论:心衰宁汤具有温阳益气、活血化瘀、养心通脉、强心利水、疏通微循环、改善心功能的作用,并可减少西药剂量,从而降低西药不良反应的发生率,提高临床疗效。

Objective：To explore the cardiac function and clinical curative effect of chronic congestive heart failure （CHF） patients treated by traditional Chinese medicine. Methods：The control group was given western medicine while the treatment group was given self- made Xinshuaining Decoction plus western medicine as control observation. Clinical efficacy evaluation regarded the improvement of cardiac function and left ventricular ejection fraction （LVEF） as the standard. Results： For 30 patients in the treatment group, 10 cases were markedly effective （33.3%）, 18 cases were effective （60.0%） ,2 cases were ineffective （6.7%） and the efficiency rate was 93.30% ;for 30 patients in the control group,8 cases were markedly effective （26.7%）,15 cases were effective （50.0%）,7 cases were ineffective （23.3%） and the efficiency rate was 76.70%. Compared with the control group,the total effective rate of the treatment group showed significant difference（x^2 = 8.06 ,P 〈 0.05 ）. At the same time, heart functions such as LVEF and heart rate were signifi- cantly improved before and after treatment and the treatment group were better than the control group（ P 〈0.05）. Conclusion ：Xinshuaining Decoction has the function of warming yang and nourishing qi, activating blood circulation to dissipate blood stasis, nourishing heart to promote blood circulation, promoting cardiac diuretic, dredging miro - circulation, improving cardiac function and the dose of medicine can be reduced in order to lower the incidence of adverse reactions of western medicine and improve clinical effect.