小儿急性肾功能衰竭182例临床特点及预后分析

Clinical characteristics and prognosis of 182 children with acute renal failure

目的探讨小儿急性肾功能衰竭(ARF)的病因、临床特点及预后。方法回顾性分析182例ARF患儿的临床资料、病因、不同治疗方式、预后情况。结果 <3岁组肾前性ARF患病率高于>3岁组,差异有统计学意义(P<0.01),同时肾前性及肾后性ARF治疗有效率明显高于肾性ARF(P均<0.01);血液净化+一般治疗组治疗有效率显著高于一般治疗组(P<0.01)。结论不同年龄段儿童ARF的病因不同,不同病因预后不一样。早期预防性和充分性的透析治疗可显著提高ARF的治愈率。

Objective The aim of this study was to assess the etiology,clinical characteristics and prognosis of acute renal failure（ARF）in children.Methods A total of 182 ARF children who admitted and diagnosed in Children＇s Hospital of Chongqing Medical University were enrolled in our study.A retrospective analysis study was performed to evaluate the clinical characteristics and prognosis of AFR in children.Results The prevalence of pre-renal ARF of the children younger than 3 years old was significantly higher than that of the children more than 3 years old（P0.01）.The effective rates of pre-renal and post-renal ARF treatments were higher than that of renal ARF treatment（P0.01）.Clinical effective rates of ARF children underwent blood purification were significantly higher than those accepted regular treatment without blood purification（P0.01）.Conclusions The etiologies of ARF were different in different ages of children.The efficacy of AFR in children due to the different etiologies.