PI3K信号通路及其抑制剂抗恶性肿瘤的研究进展
被引量:8
PI3K signaling pathway and its inhibitors in anti-cancer researches
摘要
磷脂酰肌醇-3-激酶(phosphoinositide 3-kinases,PI3K)介导的信号通路是细胞内重要信号转导通路之一,该通路调节细胞的增殖、分化、凋亡等活动。因此,PI3K被认为与人类的多种恶性肿瘤的发生、发展、转归密切相关。本文对PI3K信号通路的组成、功能及其抑制剂抗恶性肿瘤的研究进展作一综述。
出处
《实用医院临床杂志》
2011年第3期140-143,共4页
Practical Journal of Clinical Medicine
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