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PI3K信号通路及其抑制剂抗恶性肿瘤的研究进展 被引量：8

PI3K signaling pathway and its inhibitors in anti-cancer researches
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摘要 磷脂酰肌醇-3-激酶(phosphoinositide 3-kinases,PI3K)介导的信号通路是细胞内重要信号转导通路之一,该通路调节细胞的增殖、分化、凋亡等活动。因此,PI3K被认为与人类的多种恶性肿瘤的发生、发展、转归密切相关。本文对PI3K信号通路的组成、功能及其抑制剂抗恶性肿瘤的研究进展作一综述。
作者 陈正军 黄翔
机构地区 四川省医学科学院.四川省人民医院泌尿外科
出处 《实用医院临床杂志》 2011年第3期140-143,共4页 Practical Journal of Clinical Medicine
关键词 磷脂酰肌醇-3激-酶-Akt 信号转导 磷脂酰肌醇-3-激酶抑制剂 肿瘤 细胞凋亡
分类号 R737.1 [医药卫生—肿瘤]
  • 相关文献

参考文献39

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二级参考文献61

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共引文献45

同被引文献116

  • 1姜涛,姜辉,宋希双,李宪承,李泉林.前列腺癌中P53的表达及其临床意义[J].中华男科学杂志,2005,11(6):448-451. 被引量：11
  • 2阎洪涛,龚百生,董丹丹,杨红,陈照祥.p53和VEGF在前列腺癌组织中的表达及临床意义[J].现代泌尿外科杂志,2007,12(4):242-245. 被引量：9
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引证文献8

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实用医院临床杂志
2011年 第3期

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