1Minamoto T, Mai M, Ronai Z. K-ras mutation: early detection in molecular diagnosis and risk assessment of colorectal, pancreas, and lung cancers a review [ J]. Cancer Detect Prev,2000,24( 1 ) : 1-12.
2Liu WH, Wang DG. Apoptosis regulating genes in neuroendocrine tumors[J]. Histol Histopathol, 2000, 15 (3): 851-859.
3Sekine L, Takami S, Guang SG, et al. Role of epidermal growth factor receptor over expression, K-ras point mutation and c-myc amplification in the carcinogenesis of non-small cell lung cancer [J]. Oncol Rep,1998,5 (2) :351-354.
4Rodenhuis S, Slebos RJC. Clinical significance of ras oncogene activation in human lung cancer[ J ] . Cancer Res, 1992,52 ( 3 ) :2665s-2669s.
5Algarra I, Perez M, Serrano MJ, et al. C-K-ras overexpression is characteristic for metastases derived from a methylcholanthrene-induced fibro sarcoma [ J ]. Invasion Metastasis, 1999,18 ( 6 ) : 261- 270.
6Nelson HH, Ehristiani DC, Mark EJ, et al. Implications and prognostic value of K-ras mutation for early stage lung cancer in women [ J ]. J Natl Cancer Inst, 1999,91 ( 23 ) :2032-2038.
7Harizi H,Juzan M,Pitard V,et al.Cyclooxygenase-2 issued prostaglandin e(2) enhances the production of endogenous IL-10,which down regulates the dendritic cell functions[J].J Immunol,2002,168:2255-2263.
8Sharma S,Stolina M,Yang SC,et al.Tumor cyclooxygenase-2 dependent suppression of dendritic cell function[J].Clin Cancer Res,2003,9:961-968.
9Yamauchi T,Wayanabe M,Kubtoa T,et al.Cyclooxygenase-2 expression as a new marker for patients with colorectal cancer[J].Dis Colon Rectum,2002,45:98-103.
10Oshima M,Dinehuk JE,Kargman SL,et al.Suppression of intestinal polyposis in APC delta716 knockout mice by inhibition of cclooxygenase-2[J].Cell,1996,87:803-809.
4Weidner N,Folkman J,Pozza F,et al.Tumoran giogensis:a new significant and independent prognostic indicator in early stage breast carcinoma[J].J Natl Cancer Inst,1992,84:1875-1887.
5Shachaf CM,Felsher DW.Tumor dormancy and MYC inactivation:pushing cancer to the brink of normalcy[J].Cancer Res,2005,65(11):4471-4474.
