1Griffith JD,Comeau L,Rosenfield S,et al.Mammalian telomeres end in a large duplex loop[J].Cell,1999,97(4):503-514.
2Baykal A,Rosen D,Zhou C,et al.Telomerase in breast cancer:a critical evaluation[J].Adv Anat Pathol,2004,11(5):262-268.
3Hackett JA,Greider CW.Balancing instability:dual roles for telomerase and telomere dysfunction in tumorigenesis[J].Oncogene,2002,21 (4):619-626.
4Blackburn EH.Telomere states and cell fates[J].Nature,2000,408 (6808):53-56.
5Liu L,Franco S,Spyropoulos B,et al.Irregular telomeres impair meiotic synapsis and recombination in mice[J].Proc Natl Acad Sci USA,2004,101 (17):6496-6501.
6Shao R,GUO X.Human microvascular endothelial cells immortalized with human telomerase catalytic protein:a model for the study of in vitro angiogenesis[J].Biochem Biophys Res Commun,2004,321 (4):788-794.
7Lue NF,Bosoy D,Moriarty TJ,et al.Telomerase can act as a template-and RNA-independent terminal transferase[J].Proc Natl Acad Sci USA,2005,102 (28):9778-9783.
8Feldser DM,Hackett JA,Greider CW.Tdomere dysfunction and the initiation of genome instability[J].Nat Rev Cancer,2003,3 (8):623-627.
9Purev E,soprano DR,Soprano KJ.Effect of all-trans retinoic acid on telomerase activity in ovarian cancer cells[J].J Exp Clin Cancer Res,2004,23(2):309-316.
10Bodnar AG,Ouellette M,Frolkis M,et al.Extension of life-span by introduction of telomerase into normal human cells[J].Science,1998,279(5349):349-352.