咪达唑仑、芬太尼、丙泊酚联合用于无痛人工流产术效果观察

Effect observation of midazolam combined with propofol and fentanyl in painless artificial abortion

目的观察咪达唑仑、芬太尼、丙泊酚联合用于无痛人工流产术的效果。方法 400例自愿无痛人工流产患者随机分为观察组和对照组各200例。观察组采用咪达唑仑、芬太尼、丙泊酚联合麻醉,对照组采用芬太尼、丙泊酚联合麻醉,比较2组生命体征、苏醒时间、丙泊酚诱导量及总量。结果观察组患者苏醒时间为(1.50±0.37)min,对照组为(1.50±0.21)min,2组比较差异无统计学意义(P>0.05)。观察组丙泊酚诱导量及总量均低于对照组,差异有统计学意义(P<0.05)。对照组术中收缩压(SBP)、舒张压(DBP)及HR均低于术前,差异有统计学意义(P<0.05),而观察组各项指标变化差异无统计学意义(P>0.05)。结论咪达唑仑、芬太尼、丙泊酚联合用于无痛人工流产术是一种麻醉效果佳且安全的麻醉方法。

Objective To investigate the effect of midazolam combined with propofol and fentanyl in painless artificial abortion. Methods 400 patients who were voluntary to undergo painless artificial abortion were randomly divided into observation group and control group,200 cases of each.The observation group was given midazolam combined with propofol and fentanyl to make anesthesia,while the control group was given propofol and fentanyl.The vital signs,awake time,the induction amount and total amount of propofol of 2 groups were compared. Results The awake time of the observation group was （1.50±0.37）min,while that of the control group was（1.50±0.21）min,and there was no statistical significance（P0.05）.The induction amount and total amount of propofol of the observation group were respectively lower than those of the control group,and the differences were statistically significant（P0.05）.SBP,DBP and HR during the operation of the control group were respectively lower than those before operation,and the differences were statistically significant（P0.05）,while those of the observation group were of no statistical significance（P0.05）. Conclusion Midazolam combined with propofol and fentanyl is a effective and safe anesthesia way for painless artificial abortion.