大血小板比率血小板平均体积和纤维蛋白原水平与脑出血患者相关性研究

Correlation of the ratio in large platelets,mean platelet volume and fibrinogen levels in patients with cerebral hemorrhage

目的探讨脑出血患者大血小板比率(P-LCR)、血小板平均体积(MPV)、纤维蛋白原(Fg)水平与脑出血的关系。方法对137例脑卒中住院患者与65例同期门诊健康体检者进行P-LCR、MPV、Fg水平检测。结果 137例患者中,67例脑出血患者Fg水平与脑梗死患者及健康对照者差异均有统计学意义(P<0.05);P-LCR、MPV与脑梗死患者无明显差异(P>0.05),但与健康对照者相比差异有统计学意义(P<0.01)。结论 P-LCR、MPV、Fg水平和脑出血有明显的相关性。

Objective To investigate the relationship between the rate of large platelets（P-LCR）,mean platelet volume（MPV）,and fibrinogen in patients with cerebral hemorrhage.Methods Compare the detection level of P-LCR,MPV,Fg in 137 patients with stroke hospitalized patients and 65 healthy cases over the same period.Results Among the 137 cases,the level of Fg was significantly different in 67 patients of cerebral hemorrhage compared with 70 patients of cerebral infarction and 65 healthy cases（P0.05）.The levels of P-LCR,MPV were of no significant difference in 67 patients of cerebral hemorrhage compared with 70 patients of cerebral infarction（P 0.05）,but they were significantly different in 67 patients of cerebral hemorrhage compared with 65 healthy cases（P0.01）.Conclusion Plasma levels of P-LCR,MPV,Fg are strongly associated with cerebral hemorrhage.