腰围/身高比值与非肥胖者心血管危险因素聚集关系

Association Betweem Waist to Height Ratio and Clustering of Coronary Risk Factors Among Non-obese Men and Women

目的本研究旨在探讨腰围/身高比值(WHtR)这一腹型肥胖指标用于评价非肥胖者心血管危险因素聚集的价值。方法 BMI<25 kg/m2的健康体检者,测量血压、身高、体重、腰围(WC)、臀围,计算体重指标(BMI)、WHtR及腰臀围比(WHR),并检测血糖、血脂等。采用偏相关系数分析WHtR、BMI、WC及WHR与危险因素聚集的关系,受试者工作特征(receiver operator characteristic,ROC)曲线分析各肥胖指标预测危险因素聚集的效能。结果偏相关分析与显示,调整年龄的影响后,各肥胖指标与心血管危险因素聚集呈显著相关(P<0.05),男女均以WHtR的相关系数最大。ROC分析显示:针对≥2个危险因素聚集,男女性均以WHtR的曲线下面积最大。结论 WHtR是有效的预测非肥胖者心血管危险因素聚集的中心性肥胖指标。

Objective To evaluate the value of waist to height ratio（WHtR） as an abdominal obesity index for assessing metabolic risks among the non-obese individuals. Methods We compared body mass index（BMI）,waist circumference,and waist-to-height ratio（WHtR） as indices for evaluation of clustering of coronary risk factors in 610 men and 681 women with BMI25 kg/m2.Partial correlation analysis and ROC curve analysis were conducted. Results The sum of coronary risk factors was significantly correlated with all anthropometric indices（P0.05）,with the closest correlation found for WHtR.ROC analysis showed that the areas under curve（AUC） of WHtR in both sexes was the largest among the four anthropometric indices for clustering of ≥ 2 risk factors. Conclusions We propose the measurement of WHtR as a screening tool for cardiovascular risk factors in this population.WHtR measurement can provide an opportunity for evaluating clustering of coronary risk factors among non-obese men and women.