郴州市甲型H1N1流感流行态势研究

Study on Tendencies of Influenza A-H1N1 in Chenzhou

目的了解郴州市甲型H1N1流感流行特征,分析流行原因,为防控工作提供科学依据。方法收集郴州市2009-2010年甲型H1N1流感疫情、监测资料,运用描述性流行病学进行分析。结果郴州市2009-2010年报告甲型H1N1流感病例4 459例,发病率95.61/10万,其中重症病例17例(占0.38%),死亡3例,病死率0.67‰;疫情从2009年8月上旬发生输入性病例开始,发病数快速上升,11月份达到发病高峰,2010年1月份快速下降,并维持在较低水平;病例多为在校学生,占病例数的95.70%,男性发病数明显多于女性;发生暴发疫情38起,其中发生在学校36起,续发率3.98%;流感监测显示:9月份以后甲型H1N1流感病毒迅速取代季节性流感病毒,成为流行优势病毒株;甲型H1N1流感病毒感染状况调查IgG抗体阳性率32.28%。结论郴州市甲型H1N1流感疫情通过综合措施得到有效防控;通过加强监测,积极开展疫苗接种,能够有效遏制甲型H1N1流感快速传播。

Objective To investigate the epidemic characteristics and epidemic causes of influenza A-H1N1 in Chenzhou,and to provide a scientific basis for prevention and control measures. Methods Data of influenza A-H1N1 outbreaks and epidemic monitoring were collected,and then analyzed with Excel and SPSS11.5 statistical software. Results Totally 4,459 cases of influenza A-H1N1 were reported in Chenzhou during the period of 2009～2010,and the morbidity rate was 95.61/100,000;of which 17 cases were severe cases,accounting for 0.38% of the total diseased cases;3 cases were death cases,with the fatality rate of 0.67‰.The epidemic situation started from the imported case in early August 2009,and then the number of cases rapidly increased.It reached the peak in November and rapidly declined in January 2010,then remained at relatively low level.95.70% of all the cases were students,and the number of males was significantly more than that of females.There were 38 outbreaks of influenza A-H1N1,36 of which occurred in schools,with the secondary attack rate of 3.98%.Influenza surveillance showed that influenza A-H1N1 virus had quickly replaced seasonal influenza viruses,and became the predominant strain virus after September.An investigation on influenza A-H1N1 infection indicated that IgG antibody-positive rate was 32.28%. Conclusions The spread of influenza A-H1N1 virus in Chenzhou is controlled effectively through comprehensive management measures.Strengthening monitoring and actively performing vaccination can effectively restrain the rapid spread of H1N1 influenza A virus infection.