期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

沃尼妙林的合成进展 被引量：4

Research Advance of Synthesis of Valnemulin
下载PDF
导出
摘要 简要介绍了沃尼妙林的药物学、抗菌机理以及抗菌活性及毒性研究。重点阐述了沃尼妙林的3种合成方法,分析了合成方法中存在的问题,为其合成研究提供了参考。 To summary the pharmacy,mechanism,antibacterial activity and poisonousness of valnemulin.To introduce three synthetic methods of valnemulin in detail.To analyze the problems relating to the synthesis of valnemulin in order to provide a reference for the research.
作者 付江涛 赵地顺 郑连义 任培兵 刘猛帅
机构地区 河北科技大学化学与制药工程学院 石家庄焦化集团有限责任公司
出处 《河北化工》 2011年第5期16-19,共4页 Hebei Chemical Industry
关键词 抗生素 沃尼妙林 盐酸沃尼妙林 截短侧耳素 合成 antibiotic valnemulin valnemulin hydrochloride pleuromutilin synthesis
分类号 S859.796 [农业科学—临床兽医学]
  • 相关文献

参考文献17

  • 1Heilmann C,Jensen L,Jensen J S,et al.Treatment of resistant Mycoplasma infection in inmunocompromised patients with a new pleuromutilin antibiotic[J].Infect,2001,43(4):234-238.
  • 2Berner H,Vypiei H.Pleuromutilin Derivatives and Their Use[P].EP:0153277,1985-08-28.
  • 3Qiushi Huang,Jiancheng Li,et al.Residue depletion of valnemulin in swine tissues after oral administration[J].Analytica Chimica Acta,2010,664:62-67.
  • 4Poulsen S M,Karlsson M,Johansson L B,et al.The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome[J].Mol Microbiol,2001,41(5):1 091-1 099.
  • 5Hunt E.Pleuromutilin antibiotics[J].Drugs Fut,2000,25(11):1 163-1 168.
  • 6Karlsson M,Gunnarsson A,Franklin A.Susceptibility to pleuromutilins in Brachyspira(Serpulina)hyodysenteriae[J].Anim Health Res Rev,2001,2(l):59-65.
  • 7Zullo A,Hassan C,Eramo A,et al.Helicobacter pyloritherapy:what is coming?[J].Expert Opin Ther Pat,2006,16(8):1 107-1 112.
  • 8Boxall ABA,Oakes D,Ripley P,et al.The application of predictive models in the environmental risk assessment of ECONOR[J].Chemosphere,2000,40:775-781.
  • 9雷宪军,孔凡亭,胡江林,等.一种盐酸沃尼妙林的合成方法[P].中国:200910231295.2,2010-06-16.
  • 10冯德鑫,李新乐,潘强,王峥,Michael H.CHEN.盐酸沃尼妙林的合成[J].中国医药工业杂志,2010,41(4):244-246. 被引量：7

二级参考文献38

  • 1徐福亮,袁延文.介绍一种新的动物专用抗生素——盐酸沃尼妙林及其在猪病防治上的应用[J].中国动物保健,2005,7(12):40-42. 被引量：14
  • 2Poulsen S, Karlsson M, Johansson L, et al. 31ae pleuromutilin drags tiainulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome[J] .Mol Microbiol,2001,1091 - 1099.
  • 3Novartis AG. Formtdation of valnemulin: US, 6284792 [ P]. 2001 - 09 - 04.
  • 4Sandoz L. Pleuromutilin derivatives process for their preparation and their use: US,4675330[ P].1987 - 06 - 23.
  • 5陈剑慧,韩勤更,邓京,等.沃尼妙林的制备方法:中国,200810022972.5[P].2008-12-10.
  • 6PHILLIPS O A, SHARAF L H. Pleuromutilin antibacterial agents: patent review 2001-2006[J]. Expert Opin Ther Pat, 2007,17(4) :429-435.
  • 7ZULLO A, HASSAN C, ERAMO A,et al. Helicobocter pylori therapy: what is coming? [J]. Expert Opin Ther Pat, 2006,16(8) :1107-1112.
  • 8STIPKOVITS L, MILLER D, GLAVITS R, et al. Treatment of pigs experimentally infected with Mycoplasma hyopneumoniae, Pasteurella multocida, and Actinobacillus pleuropneumoniae with various antibiotics[J]. Can J Vet Res ,2001, 65(4) :213-222.
  • 9NOVARTIS ANIMAl. HEALTHY GMBH AUSTRIA. Product profile[DB/OL]. http://www.emea. europa.eu/vetdocs/ PDFs/EPAR/econor/003199en6. pdf,2002 2004.
  • 10BOXALL A B, OAKES D, RIPLEY P, et al. The application of predictive models in the environmental risk assessment of ECONOR[J]. Chemosphere,2000,40( 7) :775-781.

共引文献12

同被引文献20

  • 1徐福亮,袁延文.介绍一种新的动物专用抗生素——盐酸沃尼妙林及其在猪病防治上的应用[J].中国动物保健,2005,7(12):40-42. 被引量：14
  • 2Huang Qiushi,Li Jiancheng,Xia Lijun,et al.Residue depletion ofvalnemulin in swine tissues after oral administration[J].AnalyticaChimica Acta,2010,664(1):62-67.
  • 3Heilmann C,Jensen L,Jensen J S,et al.Treatment ofresistant mycoplasma infection in inmunocompromised patientswitha new pleuromutilin antibiotic[J].Infect,2001,43(4):234-238.
  • 4Sandoz L.Pleuromutilin derivatives process for their preparationand their use[P].US:4675330,1987-06-23.
  • 5Berner H,Vypiei H.Pleuromutilin derivatives and their use[P].EP:0153277,1985-08-28.
  • 6Koller K,Schwarz F.Formulation of valnemulin[P].US:6284792,2001-09-04.
  • 7Macher I,Austria W.Pleuromutilins[P].US:5284967,1994-02-08.
  • 8刘波,李金明,杨芳,等.沃尼妙林及其盐酸盐的制备方法:中国,101597248A[P].2009-12-09.
  • 9雷宪军,孔凡亭,胡江林,等.一种盐酸沃尼妙林的合成方法:中国,101735123A[P].2010-06-16.
  • 10Macher I. Pleuromutilins : US, 5164526 [ P ]. 1992-11 - 17.

引证文献4

二级引证文献1

河北化工
2011年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部