B超引导下卵泡抽吸纠正多囊卵巢及多囊卵巢综合征排卵障碍

TRANSVAGINAL ULTRASOUND GUIDED FOLLICULAR ASPIRATION IN THE MANAGEMENT OF ANOVULATORY INFERTILITY ASSOCIATED WITH POLYCYSTIC OVARIES AND POLYCYSTIC OVARIAN DISEASE

目的 :本文研究了卵泡抽吸对多囊卵巢及多囊卵巢综合征诱发卵巢排卵的作用及对妊娠率的影响。方法 :在连续 3个周期中经促性腺激素、绒毛膜促性腺激素卵泡刺激方案治疗无排卵的 8例多囊卵巢综合征患者和 8例多囊卵巢患者进入该研究。研究期间应用原来的卵泡刺激方案。于第一月经周期黄体期穿刺并彻底抽吸卵泡。卵泡抽吸后的连续 3个月经周期 B超监测排卵及妊娠。结果 :在多囊卵巢综合征患者 ,每个周期的排卵率为 5 5 .0 % ;在多囊卵巢患者 ,每个周期的排卵率为 68.4 %。在卵泡抽吸后多囊卵巢综合征和多囊卵巢患者均有一半获得妊娠。结论 :B超引导下卵泡抽吸可能成为对无排卵性多囊卵巢及多囊卵巢综合征患者新的治疗方法。

Objective:To assess the effect of follicular aspiration on ovulation and pregnancy rate in polycystic ovaries and polycystic ovarian disease.Methods:Eight patients with polycystic ovary disease (PCOD) and 8 patients with polycystic ovary (PCO) who failed to ovulate by the medical therapies in the previous 3 cycles were recruited into the study.The same ovarian stimulation regimen as used in the previous cycles was administered.Most of the unruptured follicles were punctured and thoroughly aspirated during the midluteal phase of the first cycle.Evidence of ovulation and subsequent pregnancy was ultrasonically monitored after the aspiration for three consecutive cylyes.Results:The ovulation rates were 55.0% per cycle in PCOD patients and 68.4% per cycle in PCO patients,respectively.Half of the patients both with PCOD and PCO achieved pregnancy within 3 cycles after the aspiration.Conclusion:The ultrasound guided follicular aspiration seems to be a new surgical method for treating anovulatory patients with PCO and PCOD.