有机锡化合物对牡蛎脂质过氧化的影响

Effects of Organotin Compounds on the Lipid Peroxidation of Oyste

比较了近海软体动物牡蛎曝露于0.5、1、2、5、10μg/L的三丁基锡(TBT)及1、10、50μg/L的一丁基锡(MBT)、二丁基锡(DBT)12、24、36、48、72、96 h后体内脂质过氧化程度的变化情况.结果显示:TBT的生物毒性明显大于MBT、DBT;TBT对牡蛎丙二醛(MDA)含量有显著诱导升高作用,并随浓度的增加和时间的延长而不断增大;牡蛎MDA的含量变化与其受TBT胁迫具有较好的相关性,可作为海洋环境有机锡污染监测的潜在生物标志物.

Effects of organotin compounds（TBT,DBT,MBT） with different concentrations（TBT：0.5,1,2,5,10 μg/L;MBT and DBT：1,10,50 μg/L） and different exposure time（12,24,36,48,72,96 h） on the lipid peroxidation of oyster were researched.The concentrations of malondialdehyde（MDA） of the oysters were determined respectively and the results show that the toxicity of TBT is significantly higher than that of MBT and DBT,and the concentrations of MDA of oysters increase after TBT exposure,and the MDA level enhances both with the increased TBT concentration and the prolonged treating time.The results also suggest that MDA concentration of the oysters could be regarded as a potential biomarker to monitor marine pollution of organtins.