外周动静脉同步换血疗法治疗重症新生儿高胆红素血症的临床研究

Clinical study of peripheral vessel exchange transfusion on treating severe neonatal hyperbilirubinemia

目的探讨外周动静脉同步换血疗法治疗重症新生儿高胆红素血症的疗效。方法对40例重症新生儿高胆红素血症行外周动静脉同步换血治疗,换血前后进行血常规、电解质、血糖、血液酸碱度及肝功能等检查。结果换血后总胆红素平均下降56.35%,间接胆红素平均下降57.46%,血气?血糖比较平稳。血常规?电解质有一定变化,无不良反应发生。结论外周动静脉同步换血是抢救重症新生儿高胆红素血症简单、安全、有效的方法。

Objective To study the effect of peripheral vessel exchange transfusion on treating severe neonatal hyperbilirubinemia.Methods 40 newborns with severe neonatal hyperbilirubinemia received peripheral synchronous artery-vein exchange transfusion,and their blood routine examination,serum electrolyte level,blood glucose level,blood PH and liver function were observed before and after exchange transfusion.Results After exchange transfusion,the average reduction ratio of total bilirubin and indirect bilirubin was 56.35% and 57.46% respectively.The blood gas and blood glucose level kept relatively stable.Although there were some changes in blood routine and serum electrolyte level,but all cases had no obvious adverse reaction.Conclusion The peripheral vessel exchange transfusion is a simple,safe and effective treatment on rescuing of severe neonatal hyperbilirubinemia.