宫瘤宁治疗子宫肌瘤的临床疗效观察

Clinical observation of therapy of Gongxuening in uterine leiomyoma

目的观察宫瘤宁胶囊治疗子宫肌瘤的临床疗效。方法采用随机对照研究方法,共观察子宫肌瘤患者113例,随机分为观察组68例,对照组45例,分别口服宫瘤宁胶囊和桂枝茯苓胶囊治疗,疗程均为3个月。结果宫瘤宁胶囊有明显缩小子宫肌瘤的功效,总有效率为80.24%,对照组为73.65%,两组相比有显著性差异(P<0.05);观察组在改善月经延长、小腹胀痛和乳房胀痛等症状方面,疗效优于对照组(P<0.05),差异有显著性;对患者血清E2的降低有明显效果,观察组优于对照组(P<0.05),差异有显著性;2组在治疗前后红细胞总数、血色素、血小板、凝血时间上均无显著性差异(P>0.05);治疗前后患者肝功能、肾功能未见异常。结论宫瘤宁胶囊治疗子宫肌瘤安全、有效,可在临床治疗子宫肌瘤患者中扩大应用,以进一步观察其大样本及远期疗效。

Objective To explore the clinical effect of Gongliuning on hysteromyoma.Methods 113 patients were randomly divided into two groups.The observation group（68 cases） was treated with Gongliuning and the control group（45 cases） with Guizhifuning.Results Gongliuning capsule had obvious effect on hysteromyoma（P0.05）.The observation group surpass the control group in reducing in the clinical symptoms（P0.05）.Conclusion Gongliuning is safe and effective to treat hysteromyoma.