乳腺癌术后化疗配合中药减毒增效的作用观察

The observation of attenuation and synergy of postoperative chemotherapy matching with traditional Chinese drug Tianzhicao capsule in breast cancer

目的观察乳腺癌术后化疗配合中药天芝草胶囊的减毒增效作用。方法 66例乳腺癌根治术后患者随机分成治疗组31例和对照组35例,对照组采用CAF及TA化疗方案,治疗组化疗同时合用天芝草胶囊口服,观察治疗前后恶心呕吐、骨髓抑制情况,对患者进行生活质量评分。结果治疗组在治疗中骨髓抑制及恶心呕吐发生率明显低于对照组(P<0.05),生存质量改善稳定率明显高于对照组(P<0.05)。结论中药天芝草胶囊对乳腺癌术后化疗有减毒增效的作用。

Objective To observe the attenuation and synergy of postoperative chemotherapy matching with traditional Chinese drug Tianzhicao capsule in patients with breast cancer.Methods 66 cases after radical mastectomy were randomly divided into treatment group（31 cases） and control group（35 cases）.The patients of control group were treated with chemotherapies of CAF and TA.Treatment group patients were given Tianzhicao capsule orally at the same time.The nausea and vomitting,the arrest of bone marrow before and after treatments and the quality of life every patient were observed.Results Myelosuppression and the occurrence of nausea and vomitting in treatment group was obviously lower than that in control group（P0.05）.The proportion of improvement and stabilization for the quality of life in treatment group was markedly higher than that in control group（P0.05）.Conclusion Traditional Chinese drug Tianzhicao capsule has attenuation and synergy to postoperative chemotherapy in breast cancer.