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妊娠期糖脂类及氨基酸代谢的研究进展 被引量:5

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摘要 妊娠是胚胎和胎儿在母体内发育成长的一种复杂而特殊的生理过程,为满足胚胎、胎儿生长发育的需要,在胎盘激素参与下,孕妇体内代谢系统发生一系列生理生化改变,目前认为从代谢的角度,妊娠期可分为两大阶段:孕早期为第一阶段,胎儿生长相对较慢,而以器官的分化发育为主,此期以合成代谢为主,母体处于养分积累的阶段;从孕中期开始,伴随激素的参与,分解代谢大量启动,胎盘转运功能也增强,以满足胎儿快速生长所需的能量和养分。下面就妊娠期糖类、脂类及氨基酸代谢方面的改变做一综述。
出处 《西部医学》 2011年第5期982-983,共2页 Medical Journal of West China
基金 国家自然基金资助项目(NO:30973203)
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参考文献20

  • 1Di Cianni G, Miccoli R, Volpe L, etal. Intermediate metabolism in normal pregnancy and in gestational diabetes[J]. Diabetes Metab Res Rev, 2003, 19(4): 259-270.
  • 2陈叙村.孕期血糖、尿糖水平86例分析[J].上海预防医学,2009,21(6):270-270. 被引量:2
  • 3Wada T, Hori S, Sugiyama M, et al. Progesterone inhibits glucose uptake by affecting diverse steps of insulin signaling in 3T3- L1 adipocytes[J]. Am J Physiol Endocrinol Metab, 2010, 298(4): E881-888.
  • 4Barbour LA, Shao J, Qiao L, et al. Human placental growth hormone causes severe insulin resistance in transgenic mice[J]. Am J Obstet Gynecol, 2002, 186(3) : 1512-517.
  • 5McIntyre HD, Chang AM, Callaway IrK, et al. Hormonal and metabolic factors associated with variations in insulin sensitivity in human pregnancy[J]. Diabetes Care, 2010, 33(2): 356-360.
  • 6薛莹,刘超.妊娠期母体胰岛的适应性变化[J].国际内科学杂志,2007,34(10):597-601. 被引量:7
  • 7耿蔷,肖小敏,潘观玉.妊娠期糖尿病患者孕中期至孕足月胰岛素抵抗变化的临床分析[J].重庆医学,2010,39(14):1860-1862. 被引量:10
  • 8Oliver MH, Jaquiery AL, Bloomfield FH, et al. The effects of maternal nutrition around the time of conception on the health of the offspring[J]. Soc Reprod Fertil Suppl, 2007, 64: 397-410.
  • 9Hod M, Yogev Y. Goals of metabolic management of gestational diabetes: is it all about the sugar[J]. Diabetes Care, 2007, 30 Suppl 2: S180-187.
  • 10Sivan E, Homko CJ, Chen X, etal. Fffect of insulin on fat metabolism during and after normal pregnancy[J]. Diabetes, 1999, 48(4): 834-838.

二级参考文献30

  • 1杨慧霞.妊娠合并糖尿病的诊治进展[J].中国实用妇科与产科杂志,2006,22(1):5-8. 被引量:93
  • 2Barbour LA.New concepts in insulin resistance of pregnancy and gestational diabetes:long-term implications for mother and offspring[J].Am J Obstet Gynecol,2003,23:545.
  • 3American College of Obstetricians and Gynecologists Committee on Practice Bulletins-Obstetrics.ACOG Practice Bulletin.Clinical management guidelines for bstetrician-gynecologists.Number 30,September 2001(replaces Technical Number 200,Detember 1994)[J].Gestational Diabetes Obstet Gynecol,2001,98:525.
  • 4Catalano PM,Tyzbir ED,Wolfe RR,et al.Carbohydrate metabolism during pregnancy in control subject and women with gestational diabetes[J].AM J Physiol,1993,264:E60.
  • 5Catalano PM,Kirwan JP,de Mouzon SH,et al.Gestational diabetes and insulin resistance:role in short-and long-term implications for mother and fetus[J].J Nutr,2003,133:1674.
  • 6Buchanan TA,Xiang AH.Gestational diabetes mellitus[J].J Clin Invest,2005,15:485.
  • 7Nelson DM.Apoptotic changes occur in syncytiotrophoblast of human placental villi where fibrin type fibrinoid is deposited at discontinuities in the villous trophoblast[J].Placnta,1996,17:387.
  • 8Homko C, Sivan E, Chen X, et al. Insulin secretion during and after pregnancy in patients with gestational diabetes mellitus. J Chin Endocrinol Metab, 2001, 86(2) :568-573.
  • 9Kirwan JP, Hauguel-De Mouzon S, Lepercq J, et al. TNF- alpha is a predictor of insulin resistance in human pregnancy. Diabetes, 2002,51 (7) :2207-2213.
  • 10Bonner-Weir S. Islet growth and development in the adult. J Mol Endocrinol, 2000,24 (3) : 297-302.

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