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子宫内膜胎盘蛋白14在子宫内膜异位症患者血清和腹水中的表达和意义 被引量：3

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摘要 目的探讨子宫内膜胎盘蛋白14(PP14)在子宫内膜异位症(EM)患者中的诊断价值。方法选取50例EM患者为研究组,对照组为体检正常的30例女性。采用ELISA法测定EM各组血清及腹水中PP14和对照组各组血清PP14水平。结果 (1)轻型EM组增生期血清PP14高于对照组增生期(P<0.05);轻型EM组分泌期血清PP14和对照组分泌期比较,差异无统计学意义(P>0.05)。重型EM组增生期和分泌期血清PP14均高于对照组(均P<0.05)。在分泌期和增生期,EM组血清PP14表达水平均为重型组高于轻型组(P<0.05)。在增生期EM组PP14腹水表达水平重型组和轻型组差异无统计学意义(P>0.05);在分泌期EM组PP14腹水表达水平重型组高于轻型组(P<0.05)。(2)EM组血清PP14和腹水PP14水平呈直线正相关(r=0.674,P<0.01)。结论 PP14在EM的发生发展中起一定作用,血清PP14可能成为诊断EM的新的血清学指标。
作者 高红艳 沈宗姬 陈继明
机构地区 苏州大学附属第三医院妇产科 苏州大学附属第一医院妇产科
出处 《苏州大学学报（医学版）》 CAS 北大核心 2011年第1期154-156,共3页 Suzhou University Journal of Medical Science
关键词 子宫内膜胎盘蛋白14 子宫内膜异位症 血清 腹水
分类号 R711.71 [医药卫生—妇产科学]
  • 相关文献

参考文献8

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二级参考文献19

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共引文献5

同被引文献33

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苏州大学学报（医学版）
2011年 第1期

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