子宫肉瘤手术治疗合并髂内动脉插管化疗

SURGERY AND TRANSCATHETER CHEMOTHERAPY OF POSTERIOR PELVIC ARTERY FOR METROSARCOMA

目的 研究提高子宫肉瘤手术治疗合并化疗的疗效，延长生存率。 方法 １９７９ 年～１９９５ 年Ⅰ～Ⅲ期子宫肉瘤３４ 例，①介入组：术前行髂内动脉插管化疗；②非介入组：术前不进行此介入化疗。两组术后化疗相同。 结果 介入组化疗后其根治术全部成功；非介入组根治术成功率３６８ ％ （７／１９）；术后复发、转移介入组为２６７ ％ （４／１５） ，非介组为６３２％ （１２／１９） 。 结论 手术治疗的Ⅰ、Ⅱ、Ⅲ期子宫肉瘤，以术前髂内动脉化疗＋ 根治术＋ 术后化疗的疗效较佳。

To improve the efficacy of surgical treatment and prolong survival of patients with transcatheter chemotherapy.METHODS Patients with transcatheter chemoinfusion of posterior pelvic artery before operation were put into the interventional therapy group, and those without transcatheter chemoinfusion were considered as non interventional therapy group. Comparative studies were carried out between the two groups from 1978 to 1995,similar chemotherapy regimens after operation were used in patients of both groups.RESULTS The success rate of radical operation in interventional therapy group was 100%,but only 36.8%(7/19) in non interventional therapy group;the rate of relapse or metastasis after operation was 26.7%(4/15) in interventional therapy group,63.2%(12/19) in non interventional therapy group.CONCLUSION The best therapy is transcatheter chemoinfusion of posterior pelvic artery before operation with radical operation and chemotherapy after operation in patients with Ⅰ,Ⅱ,Ⅲ stages of metrosarcoma.