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协和妇产科推进耐药性滋养细胞肿瘤的治愈率提升25% 被引量:1

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摘要 滋养细胞肿瘤(gestational trophoblastic neoplasms,GTN)是一系列发生于生育年龄妇女,主要与妊娠相关的恶性肿瘤,因来源于胚胎滋养细胞而得名,其中以绒癌恶性程度最高,在有效化疗药物问世前,其死亡率曾高达90%。自20世纪50年代以来,
作者 陈明雁 向阳
出处 《协和医学杂志》 2011年第2期180-180,共1页 Medical Journal of Peking Union Medical College Hospital
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  • 1丰有吉.妇产科学[M].第2版.北京:人民卫生出版社,2010:68-69.
  • 2NGAN H Y,KOHOM E I,COLE L A,et al.Throphoblastic disease[Z],2012:S130-S136.
  • 3ALAZZAM M,TIDY J,OSBOME R,et al.Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia[Z],2012:CD008891.
  • 4NGAN H Y.The practicability of FIGO 2000 staging for gestational trophoblastic neoplasia[J].International Journal of Gynecological Cancer:Official Journal of the International Gynecological Cancer Society,2004,14(2):202-205.
  • 5NGU S F,CHAN K K.Management of chemoresistant and quiescent gestational trophoblastic disease[J].Current Obstetrics and Gynecology Reports,2014,3:84-90.
  • 6Feng F.Xiang Y.Wan X.et al.Salvage combination chemotherapy with floxuridine,dactinomycin,etoposide,and vincristine(FAEV)for patients with relapsed/chemoresistant gestational trophoblastic neoplasia[J].Ann Oncol,2011,22:1588-1594.
  • 7MCNEISH I A,STRICKLAND S,HOLDEN L,et al.Low-risk persistent gestational trophoblastic disease:outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to2000[J].Journal of Clinical Oncology:Official Journal of the American Society of Clinical Oncology,2002,20(7):1838-1844.
  • 8SEBIRE N J,SECKL M J.Gestational trophobastic disease:current management of hydatidiform mole[Z].2008:A1193.
  • 9TAYLOR F,GREW T,EVERARD J,et al.The outcome of patients with low risk gestational trophoblastic neoplasia treated with single agent intramuscular methotrexate and oral folinic acid[J].European Journal of Cancer(Oxford,England:1990),2013,49(15):3184-3190.
  • 10DOLL K M,SOPER J T.Obstet gynecol Surv[J].The role of surgery in the management of gestational trophoblastic neoplasia,2013,68(7):533-542.

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