芬太尼透皮贴剂与盐酸哌替啶在恶性肿瘤患者术后镇痛中应用的效果评价及护理研究

Study on effects of Fentanyl transdermal patches and pethidine in postoperative analgesia of malig- nant tumor and nursing measures

目的探讨比较芬太尼透皮贴剂与盐酸哌替啶在恶性肿瘤患者术后镇痛应用中的效果，并研究其护理方法。方法选取2008年1月至2010年11月进行手术治疗的100例恶性肿瘤患者为研究对象，将其随机分为A组（芬太尼透皮贴剂组）和B组（盐酸哌替啶组）各50例，后将2组患者的术后2，4，8，24，48h的VAS评分及不良反应发生率、患者满意度和手术前后的血清儿茶酚胺、糖皮质激素和血糖水平进行统计及比较，并对其采取相应的护理措施。结果A组的术后2，4，8，24，48h的VAS评分均优于B组，不良反应发生率低于B组，患者满意度高于B组，手术后血清儿茶酚胺、皮质醇和血糖水平均显著低于B组。结论芬太尼透皮贴剂在恶性肿瘤患者术后镇痛应用中的效果更为稳定，广受患者好评，配合适当的护理效果明显。

Objective To study and compare the effects of Fentanyl transdermal pain patches and Pethidine in postoperative analgesia of malignant tumor and its nursing methods. Methods 100 patients with malignant tumor in our hospital from January 2008 to November 2010 were selected as research object,all the patients were randomly divided into group A （Fentanyl transdermal pain patches group） and group B （Pethidine group）with 50 cases in each group,then the VAS score 2,4,8,24 and 48h after the surgery,incidence of adverse reactions, satisfaction rate and serum catecholamine, cornsol, blood glucose before and after the surgery were analyzed and compared,and all the patients were given corresponding nursing measures. Results The VAS score of group A at 2,4,8,24 and 48h after the surgery were all better than those of group B,incidench of adverse reactions was lower than that of group B, satisfaction rate was higher than that of group B, serum catecholamine,cortisol, blood glucose after the surgery were all lower than those of group B, there were significant differences. Conclusions The effects of Fentanyl transdermal pain patches in postoperative analgesia of malignant tumor is stable, and it gets good reputation from the patients, the effects is obvious combined with nursing.