摘要
目的:探讨米非司酮配伍米索前列醇用于12-16周妊娠的效果及安全性。方法:采用随机对照研究的方法对295例孕妇(孕龄12-16周)进行观察研究,试验组145例,采用米非司酮配伍米索前列醇终止妊娠;对照组150例,采用依沙吖啶经阴道官腔内羊膜腔外插管注药终止妊娠。结果:试验组终止妊娠成功率为96.6%,明显高于对照组80.7%(P〈0.05);试验组诱导宫缩时间及胎儿胎盘娩出时间均明显短于对照组,差异有统计学意义(P〈0.05)。两组出血量比较,差异无统计学意义(P〉0.05)。结论:米非司酮配伍米索前列醇用于终止12—16周妊娠成功率高、时间短、安全简便,值得推广。
Objective:To study the clinical effect and security of Mifepristone and Misoprostol applied on the termination of 12 - 16 gestational weeks. Methods: 295 healthy pregnancy women with 12 - 16 gestational weeks were randomly divided into two groups including observation group (145 cases)with mifepristone and mlsopmstol and control group ( 150 cases) with transvaginal. Result:The success rates of abortion in observation group and control group were 96.6 % and 80.7 %, respectively( P 〈 0.05 ). There was a significant difference between the two groups in the time of Contractions time and induced abortion ( P 〈 0.05 ). There were no significant differences between groups in uterine bleeding( P 〉 0.05 ). Conclusion: The application of mifepristone and misoprostol on terimination of 12 - 16 gestatlonal weeks demanstrates advantages in high success rate, short time, simplicity, safety,it can be promotion.
出处
《医学信息(中旬刊)》
2011年第5期1689-1690,共2页
Medical Information Operations Sciences Fascicule
关键词
米非司酮
米索前列醇
依沙吖啶
终止妊娠
Mifepristone
Miseprostol
Ethacridine
Termination of pregnancy