1Steck PA,Persbous MA,Jssser SA,et al.Identification of a candidate tumor suppressor gene,MMAC1 at chromosome 10q23.3 that is mitrated in multiple advanced cancers[J].Nat Genet,1997;15:356-62.
2Machama J,Dixon JE.The tumor suppressor,PENT/MMACI,dephosphorylates the lipid second messenger,phosphatidylinositol 3,4,5 triphosphate[J].J Biol Chem,2003;273(22):13375-8.
3Lv Q,Zhao X,Song J,et al.Research on the mechanisms of PTEN gene inactivation in ovarian cancer[J].Chin J Pathol,2005;34:266-9.
7Birck A, Ahrenkiel V, Zeuthen Jet al. Mutation and allelic loss of the PTEN/MMAC1 gene in primary and metastatic mel- anoma biopsies [J].J Invest Dermatol, 2000, 114 (2) : 277.
8Harima Y, Sawada S, Nagata K et al. Mutation of the PTEN gene in advanced cervical cancer correlated with tumor progres- sion and poor outcome after radiotherapy [J]. Int J Oncol, 2001, 18 (3): 493.
9Byun DS, Cho K, Ryu BK et al. Frequent monoallelic deletion of PTEN and its reciprocal association with PIK3CA amplifica- tion in gastric carcinoma [J].Int J Cancer, 2003, 104 (3) : 318.
10Endersby R, Baker SJ. PTEN signaling in brain: neuropathol- ogy and tumorigenesis[J]. Oncogene, 2008, 27 (41): 5416.
