1998年水灾后6个受灾省病毒性肝炎的病原学调查

Investigation on Etiology of Viral Hepahtis in Six Flood Stricken Provinces of China in 1998

为了解1998年水灾后病毒性肝炎的主要流行型别，于1999年2～4月，在6个受灾省（自治区，下同）收集了就诊肝炎病人血清1135份．用酶联免疫吸附试验检测甲、乙、戊型肝炎感染指标．结果表明：（1）在水灾后的病毒性肝炎病例中，约半数为急性肝炎（45．73％），半数可能为慢性乙型肝炎（54.27％），后者少数为其它型肝炎；（2）在急性肝炎中，甲、乙、戊型肝炎分别占57.42％、30.06％和12．52％；（3）在HBsAg阳性者中，能定为急性肝炎的只占32.21％．在这里21％的急性肝炎中甲、乙、戊型肝炎的比例分别为26.18％、68.06％和5.76％，表明水灾区的急性病毒性肝炎以甲型肝炎为主，慢性肝炎以乙型肝炎为主．上述两种类型是水灾后预防的重点。

In order to investigate the major epidendc types of viral hepatitis after theflood strike in 1998 in China, we collected 1 135 serum samples of hepatitis patients fromhospitals of 6 flood stricken provinces (the autonomous region, the same below) in Februa-ry ~April 1999, and tested the samples for hepatitis infectious markers, IgM of HAV, HBcand HEV by ELISA. The results showed that ① Half of the hepatitis cases after floodstrike were acute hepatitis (45.75%), the other half were mostly chronic hepatitis B with afew of other types of hepatitis, ② Of the acute hepatitis, hepatitis A, B and E accountedfor 57.42%, 30.06% and 12.52% respectively, ③ In HBsAg positive hepatitis cases, 32.21 %of them could be determined as acute hepatitis, among them the lgM positivity of hepatitisA, B and E were 26. 18%, 68.08% and 5.76% respectively. It demonstrated that in the floodstricken provinces in 1998, the acute viral hepatitis was chiefly of hepatitis A and the chron-ic viral hepatitis was the hepatitis B. These two types of hepatitis may be considered as theimportant preventive objects after flood strike.