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368例甲状旁腺功能亢进症的外科治疗 被引量:9

Surgical treatment for hyperparathyroidism in 368 patients
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摘要 目的 分析甲状旁腺功能亢进患者的手术治疗和病理特征.方法 回顾性分析1974年10月至2009年1月间368例在北京协和医院接受手术治疗的甲状旁腺功能亢进患者的临床资料.结果 368例患者接受手术治疗,女性249例(67.7%),男性119例(32.3%).原位甲状旁腺318例(86.4%),异位甲状旁腺50例(13.6%).病理诊断为腺瘤264例(71.7%),增生91例(24.7%),腺癌11例(3.0%),囊肿2例(0.6%).冰冻切片与石蜡病理符合率86.5%.257例(68.0%)患者术后有低钙表现,159例患者(66.0%)一周内恢复.结论 绝大多数甲状旁腺功能亢进患者病理诊断为腺瘤.异位甲状旁腺相当常见,应引起手术医师足够重视. Objective To analyze the surgical treatment and pathological manifestations in patients with hyperparathyroidism. Methods The clinical data of 368 patients undergoing parathyroidectomy with hyperparathyroidism in Peking Union Medical College Hospital between Oct 1974 and Jan 2009 were retrospectively analyzed. Results 368 cases underwent parathyroidectomy. There were 249 women (67.7%) and 119 men (32. 3% ). Parathyroid lesions were located in normal positions in 318 cases (86. 4% ), and in ectopic positions in 50 cases (13.6%). The pathology of 264 cases (71.7%) was adenoma, 91cases (24.7%) was hyperplasia, 11 cases (3.0%) was carcinoma, and two cases was parathyroid cyst. Postoperatively 257 cases (68.0%) presented with hypocalcaemia, and 159 cases (66. 0% ) recovered within 7 days. Conclusions The main pathological diagnosis was adenoma. It is common for a ectopic parathyroid gland in which a parathyroid lesion is located.
出处 《中华普通外科杂志》 CSCD 北大核心 2011年第4期289-291,共3页 Chinese Journal of General Surgery
关键词 甲状旁腺功能亢进症 甲状旁腺切除术 甲状旁腺素 Hyperparathyroidisna Parathyroidectomy Parathyroid hormone
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