96例乳腺癌患者放射性核素全身骨显像分析

Whole body radionuclide bone imagical analysis in 96 patients with breast cancer

目的 探讨乳腺癌的转移规律，评价临床分期及病理类型与骨转移的关系。方法 对９６ 例乳腺癌术后患者进行了放射性核素全身骨显像。结果 骨转移５５ 例，其中多发性骨转移４４ 例，骨转移的部位以肋骨为多见，其次是脊柱、骨盆。Ⅰ～Ⅳ期乳腺癌的骨转移率，分别是１３ ．３ ％ 、５０％ 、６５．２ ％ 和９４．４ ％ 。在浸润性非特殊型乳腺癌中，髓样癌、单纯癌、腺癌、浸润性导管癌及浸润性小叶癌骨转移的发生率，分别为８５．７％ 、６６ ．７ ％ 、５４．５ ％ 、３９ ．３ ％ 、３３ ．３ ％ 。结论 Ⅰ～Ⅳ期乳腺癌的骨转移的发生率呈明显增高趋势；常见的单纯癌骨转移率高于浸润性导管癌。

Objectives To explore characteristsis skeletal metastases of breast cancer,and investigate the relation between clinical stage and histopthology.Methods Ninety-six patients with breast cancer were pathological confirmed and whole body radiounclide bone imaging was performed.Results In patients with the disease,55 patients had skeletal metastases.Among them mnltiple metastases lessions occured in 44 patients.The first site of skeletal metastases was ribs,and other sites were spine,peluis.The rates of incidence of skeletal of stage form Ⅰ to Ⅳwere 13.3%,52.5%,63.6%,94.4% respectively.In infiltrative non-specific carcinoma,rates of incidence of selectal metastasea of encephaloid carcinoma,carcinoma simple,adenocarcinoma,infltrative ductal carcinomaand infltrativel lobular carcinoma were 85.7%,66.7%,54.5%,39.3%,33.3% respectively.Conclusions There is a tendency that the rate of incidence of skeletal is increasing with the clinicae stage of Ⅰ to Ⅳ in breast cancer.The rate of incidence of skeletal metastasea in xarxinoma simples in comman is higher than that infitrative ductal carcinoma