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Colorectal cancer and 18FDG-PET/CT:What about adding the T to the N parameter in loco-regional staging? 被引量:5

Colorectal cancer and 18FDG-PET/CT:What about adding the T to the N parameter in loco-regional staging?
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摘要 AIM:To evaluate whether FDG-positron emission tomography(PET)/computed tomography(CT)may be an accurate technique in the assessment of the T stage in patients with colorectal cancer.METHODS:Thirty four consecutive patients(20 men and 14 women;mean age:63 years)with a histologically proven diagnosis of colorectal adenocarcinoma and scheduled for surgery in our hospital were enrolled in this study.All patients underwent FDG-PET/CT preoperatively.The primary tumor site and extent were evaluated on PET/CT images.Colorectal wall invasion was analysed according to a modified T classification that considers only three stages(≤T2,T3,T4).Assessment of accuracy was carried out using 95%confidence intervals for T.RESULTS:Thirty five/37(94.6%)adenocarcinomas were identified and correctly located on PET/CT images.PET/CT correctly staged the T of 33/35 lesions identified showing an accuracy of 94.3%(95%CI:87%-100%).All T1,T3 and T4 lesions were correctly staged,while two T2 neoplasms were overstated as T3.CONCLUSION:Our data suggest that FDG-PET/CT may be an accurate modality for identifying primary tumor and defining its local extent in patients with colorectal cancer. AIM:To evaluate whether FDG-positron emission tomography(PET)/computed tomography(CT)may be an accurate technique in the assessment of the T stage in patients with colorectal cancer.METHODS:Thirty four consecutive patients(20 men and 14 women;mean age:63 years)with a histologically proven diagnosis of colorectal adenocarcinoma and scheduled for surgery in our hospital were enrolled in this study.All patients underwent FDG-PET/CT preoperatively.The primary tumor site and extent were evaluated on PET/CT images.Colorectal wall invasion was analysed according to a modified T classification that considers only three stages(≤T2,T3,T4).Assessment of accuracy was carried out using 95%confidence intervals for T.RESULTS:Thirty five/37(94.6%)adenocarcinomas were identified and correctly located on PET/CT images.PET/CT correctly staged the T of 33/35 lesions identified showing an accuracy of 94.3%(95%CI:87%-100%).All T1,T3 and T4 lesions were correctly staged,while two T2 neoplasms were overstated as T3.CONCLUSION:Our data suggest that FDG-PET/CT may be an accurate modality for identifying primary tumor and defining its local extent in patients with colorectal cancer.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第11期1427-1433,共7页 世界胃肠病学杂志(英文版)
关键词 Cancer COLORECTAL Positron emission tomography/computed tomography STAGING 大肠癌 局部区域 正电子发射断层扫描 计算机断层扫描 CT图像 PET 平均年龄 可信区间
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  • 4Storto, G,Nicolai, E,Salvatore, M.[^sup 18^F]FDG-PET-CT for early monitoring of tumor response: when and why[J]. The Quarterly Journal of Nuclear Medicine and Molecular Imaging . 2009 (2)
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  • 9Charlotte Kessel,Constantinus Buckens,Maurice Bosch,Maarten Leeuwen,Richard Hillegersberg,Helena Verkooijen.Preoperative Imaging of Colorectal Liver Metastases After Neoadjuvant Chemotherapy: A Meta-Analysis[J]. Annals of Surgical Oncology . 2012 (9)
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