胞必佳治疗恶性胸腔积液近期疗效观察

Immediate effect of N CWS in treatment of malignant pleural effusion

目的：评价胞必佳（ Ｎ Ｃ Ｗ Ｓ） 联合全身化疗及单纯全身化疗对恶性胸腔积液的治疗作用。方法：７５ 例恶性胸腔积液患者随机分为联合组（ 胞必佳胸腔内注射加全身化疗） 及单用全身化疗组两组。结果：联合组的有效率为９１ ．９ ％ ，优于单用全身化疗组的有效率５７ ．９ ％ （ Ｐ＜ ０ ．０１） 。结论：胞必佳胸腔内注射联合全身化疗优于单纯化疗控制胸水的疗效，值得临床推广应用。

Objective:To evaluate results of N CWS(nocardia rubra cell wall skeleton) treatment through intravenous route or in combination with intrapleural instillation in malignant pleural effusion.Methods:Seventy five cases of malignant pleural effusion were divided at random into intrapleural and intravenous in combination treated group and intravenous alone treated group.Results:The effective rate of intrapleural and intravenous in combination treated group was 91.9% and the effective rate of intravenous alone treated group was 57.9%.The difference between two groups was sigificant( P <0.01).Conclusions:The effect of intrapleural and intravenous treatment of N CWS in combination is better than intravenous treament alone in malignant pleural effusion.Therefore it is a method of choice in clinic.