全麻中成人与小儿血乳酸、血糖的变化

Changes of lactate and glucose level in blood in adults and children under general anesthesia

目的：探讨全麻中成人与小儿血乳酸、血糖变化的差异。方法：择期全麻手术的小儿、成人各２０ 例，分别于麻醉诱导后即刻及麻醉后６０ ｍｉｎ 测定血乳酸、血糖值。结果：麻醉后６０ ｍｉｎ ，成人组血糖和乳酸均明显较诱导后升高（ Ｐ＜ ０ ．０１） ；小儿组血糖和乳酸亦均比诱导后明显升高（ Ｐ＜ ０ ．０１） 。小儿组血糖及乳酸均高于成人组（ Ｐ＜ ０ ．０１） 。结论：全麻中成人与小儿血乳酸值的变化差异较大，小儿乳酸值增高明显大于成人，与小儿应激反应强烈对麻醉和手术的耐受性较差有关。

Objective:To detect the changes of lactate and glucose level in blood in adults and children under general anesthesia.Methods:Patients(20 adults and 20 children) were selected for surgical operation under general anesthesia.Blood samples were collected for measurement of lactate and glucose level in blood right after anesthesia and 60 minutes after anesthesia.Results:The blood lactate and glucose level increased significantly 60 minutes after anesthesia in both groups.Blood lactate in children was significantly higher than in adults( P < 0.01). Conclusions:The changes in blood lactate level under anesthesia differences greatly between adults and children.Blood lactate level in children was significantly higher than adults.The reason is that the children is stronger in response to stress and less tolerated to anesthesia and surgical manipulation .