靶控输注丙泊酚对高原高血压病人全麻诱导时血压变异性的影响

Effects of Target Controlled Infusion of Propofol on the Blood Pressure Variability of Patients with High Altitude Hypertension during General Anesthesia Induction

目的观察丙泊酚靶控输注对高原高血压病人全麻诱导期血压变异性的影响.方法 40例全麻插管高原高血压病人随机分为两组,靶控组采用Diprifusor/TCI系统按靶浓度诱导给药,普通组人工推注丙泊酚.观察有创血压,计算血压变异性.结果靶控组血压变异性明显低于普通组(P<0.05).结论丙泊酚TCI对高原高血压病人全麻诱导期血压变异性影响小,诱导过程血压波动较小.

Objective To observe the effects of target controlled infusion （TCI） of propufol on the blood pressure variability of patients with high altitude hypertension during general anesthesia induction. Methods Forty patients with high altitude hypertension were randomly divided into two groups： TCI group （n = 20） and normal group （n = 20）. Patients in group TCI were given Propofol by using Diprifusor/TCI system according target concentration, and patients in normal group was injected manually with Propofol. Invasive blood pressure was recorded, and the bluod pressure variability was calculated. Result The blood pressure variability of patients in TCI group was obviously less than that in normal group （P〈 0.05）. Conclusion TCI of propofol with Diprifusor syslem can decrease the blood pressure variability of patients with high altitude hypertensive during general anesthesia induction.